Evidence map›Paper›PMID 33319337›Full record

ArticleClinical oral investigations2021

Do bleaching gels affect the stability of the masking and caries-arresting effects of caries infiltration-in vitro.

Ellen Elisabeth Jansen, Hendrik Meyer-Lueckel, Marcella Esteves-Oliveira, Richard Johannes Wierichs

Open access · hybridAbstract read
In one paragraph

Article in Clinical oral investigations, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 28 citations in OpenAlex.

  1. In Vitro Effects of Combining Resin Infiltration and At-Home Bleaching on Hydrogen Peroxide Penetration, Color Change and Enamel Morphology.Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Ellen Elisabeth JansenClinic for Operative Dentistry, Periodontology and Preventive Dentistry, RWTH Aachen University, Pauwelsstraße 30, 52074, Aachen, Germany. ejansen@ukaachen.de.ORCID http://orcid.org/0000-0001-6019-4052
Hendrik Meyer-LueckelDepartment of Restorative, Preventive and Pediatric Dentistry, University of Bern, Freiburgstrasse 7, 3010, Bern, Switzerland.
Marcella Esteves-OliveiraClinic for Operative Dentistry, Periodontology and Preventive Dentistry, RWTH Aachen University, Pauwelsstraße 30, 52074, Aachen, Germany.
Richard Johannes WierichsDepartment of Restorative, Preventive and Pediatric Dentistry, University of Bern, Freiburgstrasse 7, 3010, Bern, Switzerland.
RWTH Aachen University · DEUniversity of Bern · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe aim of this study was to evaluate the influence of different bleaching gels on the masking and caries-arresting effects of infiltrated and non-infiltrated stained artificial enamel caries lesions. MATERIALS AND

methodsBovine enamel specimens (n = 240) with each two sound areas (SI and SC) and each two lesions (DI and DC) were infiltrated (DI and SI), stained (1:1 red wine-coffee mixture,70 days), and randomly distributed in six groups to be bleached with the following materials: 6%HP (HP-6), 16%CP (CP-16), 35%HP (HP-35), 40%HP (HP-40), and no bleaching (NBl,NBl-NBr). Subsequently, specimens were pH-cycled (28 days, 6 × 60 min demineralization/day) and all groups except NBl-NBr were brushed with toothpaste slurry (1.100 ppm, 2×/day, 10 s). Differences in colorimetric values (ΔL, ΔE) and integrated mineral loss (ΔΔZ) between baseline, infiltration, staining, bleaching, and pH cycling were calculated using photographic and transversal microradiographic images.

resultsAt baseline, significant visible color differences between DI and SC were observed (ΔE

conclusionsUnder the conditions chosen, the tested materials could satisfactorily bleach infiltrated and non-infiltrated stained enamel. Furthermore, bleaching did not affect the caries-arresting effect of the infiltration. CLINICAL RELEVANCE: The present study indicates that bleaching is a viable way to satisfactorily recover the appearance of discolored sound enamel and infiltrated lesions.

Indexed as

Dental CariesTooth BleachingTooth Bleaching AgentsAnimalsCattleDental Caries SusceptibilityDental EnamelGelsHydrogen PeroxideMicroradiographyGelsHydrogen PeroxideTooth Bleaching AgentsAestheticsBleachingCaries infiltrationDemineralizationEnamelIn vitroStainingWhite spot lesions

Identifiers

PMID33319337
PMCPMC8137601
OpenAlexW3111992417

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.