Evidence map›Paper›PMID 33319330›Full record

ReviewEuropean radiology2021

Dual-energy computed tomography in acute ischemic stroke: state-of-the-art.

Stephanie Mangesius, Tanja Janjic, Ruth Steiger, Lukas Haider, Rafael Rehwald, Michael Knoflach, Gerlig Widmann, Elke Gizewski, Astrid Grams

Registry-linked trialOpen access · hybridAbstract readReview
In one paragraph

Review in European radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05675774 (Dual Energy CT for Confirming Hemorrhagic Transformation After Thrombectomy for Patients With Acute Ischemic Stroke), which is not on this map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05675774 nacompletednot on this mapstarted 2023, after this paper: background citation

Dual Energy CT for Confirming Hemorrhagic Transformation After Thrombectomy for Patients With Acute Ischemic Stroke

TypeinterventionalSponsorUniversity of ManitobaRan2023 to 2025Enrolled189ConditionsStroke, Ischemic, Tomography, X-Ray ComputedArmsDual Energy CT
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Current state and advancements of imaging in acute ischemic stroke: a practical review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Innovative applications of advanced nanomaterials in cerebrovascular imaging.Frontiers in bioengineering and biotechnology · 2024
    Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Stephanie MangesiusDepartment of Neuroradiology, Medical University of Innsbruck, Innsbruck, Austria.
Tanja JanjicDepartment of Neuroradiology, Medical University of Innsbruck, Innsbruck, Austria. tanja.janjic@i-med.ac.at.ORCID http://orcid.org/0000-0003-3524-8332
Ruth SteigerDepartment of Neuroradiology, Medical University of Innsbruck, Innsbruck, Austria.
Lukas HaiderNMR Research Unit, Queens Square MS Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Science, University College London, London, UK.
Rafael RehwaldInstitute of Neurology, University College London, London, UK.
Michael KnoflachDepartment of Neurology, Medical University of Innsbruck, Innsbruck, Austria.
Gerlig WidmannDepartment of Radiology, Medical University of Innsbruck, Innsbruck, Austria.
Elke GizewskiDepartment of Neuroradiology, Medical University of Innsbruck, Innsbruck, Austria.
Astrid GramsDepartment of Neuroradiology, Medical University of Innsbruck, Innsbruck, Austria.
Innsbruck Medical University · ATNational Hospital for Neurology and Neurosurgery · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dual-energy computed tomography (DECT) allows distinguishing between tissues with similar X-ray attenuation but different atomic numbers. Recent studies demonstrated that this technique has several areas of application in patients with ischemic stroke and a potential impact on patient management. After endovascular stroke therapy (EST), hyperdense areas can represent either hemorrhage or contrast staining due to blood-brain barrier disruption, which can be differentiated reliably by DECT. Further applications are improved visualization of early infarctions, compared to single-energy computed tomography, and prediction of transformation into infarction or hemorrhage in contrast-enhancing areas. In addition, DECT allows detection and evaluation of the material composition of intra-arterial clots after EST. This review summarizes the clinical state-of-the-art of DECT in patients with stroke, and features some prospects for future developments. KEY POINTS: • Dual-energy computed tomography (DECT) allows differentiation between tissues with similar X-ray attenuation but differentatomic numbers. • DECT has several areas of application in patients with ischemic stroke and a potential impact on patient management. • Prospects for future developments in DECT may improve treatment decision-making.

Indexed as

Brain IschemiaIschemic StrokeStrokeHumansTomography, X-Ray ComputedBrain ischemiaHemorrhageStrokeThrombosisTomography, X-ray computed

Identifiers

PMID33319330
PMCPMC8128835
OpenAlexW3112561076

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.