Evidence map›Paper›PMID 33319321›Full record

Observational studyEuropean radiology experimental2020

Chest x-ray severity score in COVID-19 patients on emergency department admission: a two-centre study.

Cristian Giuseppe Monaco, Federico Zaottini, Simone Schiaffino, Alessandro Villa, Gianmarco Della Pepa, Luca Alessandro Carbonaro, Laura Menicagli, Andrea Cozzi, Serena Carriero, Francesco Arpaia and 4 more

Erratum issued Registry-linked trialOpen access · goldAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in European radiology experimental, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT04834934 (Artificial Intelligence - SARS-CoV-2 Risk Evaluation), which is not on this map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
1.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04834934 completednot on this map

Artificial Intelligence - SARS-CoV-2 Risk Evaluation

TypeobservationalSponsorIRCCS San RaffaeleRan2020 to 2021Enrolled2,000ConditionsCovid19
3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 64 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Cristian Giuseppe MonacoUnit of Radiology, IRCCS Policlinico San Donato, Via Rodolfo Morandi 30, 20097, San Donato Milanese, Italy.
Federico ZaottiniUnit of Radiology, Ospedale Lavagna, Via Don Giovanni Battista Bobbio 25, 16033, Lavagna, Italy.
Simone SchiaffinoUnit of Radiology, IRCCS Policlinico San Donato, Via Rodolfo Morandi 30, 20097, San Donato Milanese, Italy. schiaffino.simone@gmail.com.ORCID http://orcid.org/0000-0003-4243-888X
Alessandro VillaUnit of Radiology, Ospedale Lavagna, Via Don Giovanni Battista Bobbio 25, 16033, Lavagna, Italy.
Gianmarco Della PepaPostgraduate School in Radiodiagnostics, Università degli Studi di Milano, Via Festa del Perdono 7, 20122, Milan, Italy.
Luca Alessandro CarbonaroUnit of Radiology, IRCCS Policlinico San Donato, Via Rodolfo Morandi 30, 20097, San Donato Milanese, Italy.
Laura MenicagliUnit of Radiology, IRCCS Policlinico San Donato, Via Rodolfo Morandi 30, 20097, San Donato Milanese, Italy.
Andrea CozziDepartment of Biomedical Sciences for Health, Università degli Studi di Milano, Via Luigi Mangiagalli 31, 20133, Milan, Italy.
Serena CarrieroPostgraduate School in Radiodiagnostics, Università degli Studi di Milano, Via Festa del Perdono 7, 20122, Milan, Italy.
Francesco ArpaiaPostgraduate School in Radiodiagnostics, Università degli Studi di Milano, Via Festa del Perdono 7, 20122, Milan, Italy.
Giovanni Di LeoUnit of Radiology, IRCCS Policlinico San Donato, Via Rodolfo Morandi 30, 20097, San Donato Milanese, Italy.
Davide AstengoUnit of Radiology, Ospedale Lavagna, Via Don Giovanni Battista Bobbio 25, 16033, Lavagna, Italy.
Ilan RosenbergUnit of Radiology, Ospedale Lavagna, Via Don Giovanni Battista Bobbio 25, 16033, Lavagna, Italy.
Francesco SardanelliUnit of Radiology, IRCCS Policlinico San Donato, Via Rodolfo Morandi 30, 20097, San Donato Milanese, Italy.
IRCCS Policlinico San Donato · ITUniversity of Milan · ITAzienda Unità Sanitaria Locale Della Romagna · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntegration of imaging and clinical parameters could improve the stratification of COVID-19 patients on emergency department (ED) admission. We aimed to assess the extent of COVID-19 pulmonary abnormalities on chest x-ray (CXR) using a semiquantitative severity score, correlating it with clinical data and testing its interobserver agreement.

methodsFrom February 22 to April 8, 2020, 926 consecutive patients referring to ED of two institutions in Northern Italy for suspected SARS-CoV-2 infection were reviewed. Patients with reverse transcriptase-polymerase chain reaction positive for SARS-CoV-2 and CXR images on ED admission were included (295 patients, median age 69 years, 199 males). Five readers independently and blindly reviewed all CXRs, rating pulmonary parenchymal involvement using a 0-3 semiquantitative score in 1-point increments on 6 lung zones (range 0-18). Interobserver agreement was assessed with weighted Cohen's κ, correlations between median CXR score and clinical data with Spearman's ρ, and the Mann-Whitney U test.

resultsMedian score showed negative correlation with SpO

conclusionsProposed CXR pulmonary severity score in COVID-19 showed moderate to almost perfect interobserver agreement and significant but weak correlations with clinical parameters, potentially furthering CXR integration in patients' stratification.

Indexed as

AgedCOVID-19Emergency Service, HospitalFemaleHumansItalyMaleMiddle AgedPneumonia, ViralRadiography, ThoracicRetrospective StudiesSARS-CoV-2Sensitivity and SpecificitySeverity of Illness IndexChest x-rayCOVID-19COVID-19 diagnostic testingDiagnostic imagingSeverity score

Identifiers

PMID33319321
PMCPMC7735892
OpenAlexW3112767349

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.