Evidence map›Paper›PMID 33319195›Full record

ArticleKidney medicine

Performance of Glomerular Filtration Rate Estimating Equations Before and After Bariatric Surgery.

Alex R Chang, Jason George, Andrew S Levey, Josef Coresh, Morgan E Grams, Lesley A Inker

Open access · goldAbstract read
In one paragraph

Article in Kidney medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 33 citations in OpenAlex.

  1. Trial
  2. Indexing for body surface area when assessing kidney function.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2026
    Review
  3. Review
  4. Measurement, Estimation, and Correlates of the GFR before and after Bariatric Surgery.Journal of the American Society of Nephrology : JASN · 2026
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. How to assess kidney outcomes in obese people with substantial weight loss: the case of GLP1- and dual-receptor agonists.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2024
    Article
  10. Article
  11. Obesity and glomerular filtration rate.International urology and nephrology · 2024
    Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Glomerular hyperfiltration.Nature reviews. Nephrology · 2022
    Review
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Alex R ChangKidney Health Research Institute, Geisinger, Danville, PA.
Jason GeorgeDepartment of Population Health Sciences, Geisinger, Danville, PA.
Andrew S LeveyDivision of Nephrology, Tufts Medical Center, Boston, MA.
Josef CoreshWelch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins University, Baltimore, MD.
Morgan E GramsWelch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins University, Baltimore, MD.
Lesley A InkerDivision of Nephrology, Tufts Medical Center, Boston, MA.
Johns Hopkins University · USTufts Medical Center · USGeisinger Health System · USGeisinger Neuroscience Institute · US

Funding

Estimating GFR from a Panel of Endogenous Filtration Markers (Panel eGFR)R01DK097020 · NIDDK · TUFTS MEDICAL CENTER · PI LEVEY, ANDREW S · 2012 to 2014
$1.9M
Morbid Obesity, Bariatric Surgery, and Kidney FunctionK23DK106515 · NIDDK · GEISINGER CLINIC · PI CHANG, ALEXANDER R · 2015 to 2019
$890k
NIDDK NIH HHS K23 DK106515NIDDK NIH HHS R01 DK097020
6 · The paper itself

Abstract

RATIONALE &

objectiveEvaluation of glomerular filtration rate (GFR) is challenging in adults undergoing bariatric surgery because creatinine and cystatin C levels are influenced by changes in muscle and fat mass. Additionally, indexing of GFR by body surface area (BSA) may by affected by decreases in BSA. STUDY

designProspective observational study. SETTING &

participants27 adults with body mass index (BMI) ≥ 35 kg/m OUTCOMES: Indexed and nonindexed GFRs measured (mGFRs) using plasma iohexol clearance, indexed and nonindexed estimated GFR (eGFR) based on levels of creatinine, cystatin C, or both from Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equations. ANALYTIC APPROACH: Bias and percent of estimates within 20% and 30% of mGFR (P

resultsMean presurgery BMI was 49.5 (SD, 9.4) kg/m LIMITATIONS: Small, mostly white sample.

conclusionsChanges in indexed and nonindexed GFRs may be discordant after bariatric surgery in adults because of decreases in BSA. Indexed and nonindexed eGFR

Indexed as

Bariatric surgerybody surface areaCKD-EPIcreatininecystatin Cfiltration markersglomerular filtration rateobesityweight loss

Identifiers

PMID33319195
PMCPMC7729215
OpenAlexW3092700921

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.