ArticleiScience2021
Transcriptional response modules characterize IL-1β and IL-6 activity in COVID-19.
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Article in iScience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
What it found
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Who cites it
24 citing papers in PubMed, 35 citations in OpenAlex.
- Profiling short-term longitudinal severity progression and associated genes in COVID-19 patients using EHR and single-cell analysis.Scientific reports · 2025Article
- Association Between Genetic Variants inDiagnostics (Basel, Switzerland) · 2025Article
- SARS-CoV-2 infection as a model to study the effect of cinnamaldehyde as adjuvant therapy for viral pneumonia.Journal of inflammation (London, England) · 2023Article
- A myeloid program associated with COVID-19 severity is decreased by therapeutic blockade of IL-6 signaling.iScience · 2023Article
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- The multifaceted nature of IL-10: regulation, role in immunological homeostasis and its relevance to cancer, COVID-19 and post-COVID conditions.Frontiers in immunology · 2023Review
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- Gene Networks of Hyperglycemia, Diabetic Complications, and Human Proteins Targeted by SARS-CoV-2: What Is the Molecular Basis for Comorbidity?International journal of molecular sciences · 2022Article
- Circulatory Exosomes from COVID-19 Patients Trigger NLRP3 Inflammasome in Endothelial Cells.mBio · 2022Article
- HYGIEIA: HYpothesizing the Genesis of Infectious Diseases and Epidemics through an Integrated Systems Biology Approach.Viruses · 2022Article
- A Definitive Prognostication System for Patients With Thoracic Malignancies Diagnosed With Coronavirus Disease 2019: An Update From the TERAVOLT Registry.Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer · 2022Article
- Soluble IL-2R Levels at Baseline Predict the Development of Severe Respiratory Failure and Mortality in COVID-19 Patients.Viruses · 2022Article
- Inhalation of nebulized omega-3 fatty acids mitigate LPS-induced acute lung inflammation in rats: Implications for treatment of COPD and COVID-19.Prostaglandins, leukotrienes, and essential fatty acids · 2022Article
- Article
- COVIDomics: The Proteomic and Metabolomic Signatures of COVID-19.International journal of molecular sciences · 2022Review
- Differentially Expressed Genes Study Shown Potential for BCG Stimulation in Reducing the Severity of COVID-19.International journal of inflammation · 2022Article
- Interleukin-1β and Interleukin-10 Profiles and Ratio in Serum of COVID-19 Patients and Correlation with COVID-19 Severity: A Time Series Study.International journal of general medicine · 2022Article
- Single-cell multiomics revealed the dynamics of antigen presentation, immune response and T cell activation in the COVID-19 positive and recovered individuals.Frontiers in immunology · 2022Article
- C-reactive protein-guided use of procalcitonin in COVID-19.JAC-antimicrobial resistance · 2021Article
- Immunomodulation and Reduction of Thromboembolic Risk in Hospitalized COVID-19 Patients: Systematic Review and Meta-Analysis of Randomized Trials.Journal of clinical medicine · 2021Review
Corrections and comments
- Update of
Authors and funding
9 authors at 4 institutions in 2 countries.
Lucy C K BellDivision of Infection & Immunity, University College London, Cruciform Building, Gower Street, London WC1E 6BT, UK.
Cem MeydanThe HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA.
Jacob KimHerbert Irving Comprehensive Cancer Center, Columbia University, New York, NY, USA.
Jonathan FooxThe HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA.
Daniel ButlerThe HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA.
Christopher E MasonThe HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA.
Sagi D ShapiraHerbert Irving Comprehensive Cancer Center, Columbia University, New York, NY, USA.
Mahdad NoursadeghiDivision of Infection & Immunity, University College London, Cruciform Building, Gower Street, London WC1E 6BT, UK.
Gabriele PollaraDivision of Infection & Immunity, University College London, Cruciform Building, Gower Street, London WC1E 6BT, UK.
Cornell University · USColumbia University Irving Medical Center · USRoyal London Hospital · GBRoyal Free London NHS Foundation Trust · GB
Funding
Systematic pharmacological targeting of the core mechanisms responsible for maintaining cancer cell stateU54CA209997 · NCI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI CALIFANO, ANDREA, HONIG, BARRY H · 2016 to 2021
$10.9MSystematic Identification and Pharmacological Targeting of Tumor Dependencies for Precision Cancer MedicineU01CA217858 · NCI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI CALIFANO, ANDREA · 2017 to 2021
$6.1MMetagenomic profiling of urinary cell-free DNA to monitor urinary tract infection after kidney transplantationR01AI151059 · NIAID · CORNELL UNIVERSITY · PI DADHANIA, DARSHANA, DE VLAMINCK, IWIJN · 2020 to 2024
$3.4MThe Spatiotemporal Landscape of the Human Brain EpitranscriptomeR01MH117406 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI MASON, CHRISTOPHER EDWARD · 2018 to 2022
$3.3MQuantitative Studies of influenza EvolutionR01GM109018 · NIGMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SHAPIRA, SAGI · 2014 to 2019
$2.6MMapping the RNA modification N6-methyladenosine during Zika virus infectionR21AI129851 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI HORNER, STACY MICHELLE, MASON, CHRISTOPHER EDWARD · 2017 to 2018
$469kNCI NIH HHS U01 CA217858NCI NIH HHS U54 CA209997NIAID NIH HHS R01 AI151059NIAID NIH HHS R21 AI129851NIGMS NIH HHS R01 GM109018NIMH NIH HHS R01 MH117406Wellcome Trust
Abstract
Dysregulated IL-1β and IL-6 responses have been implicated in the pathogenesis of severe Coronavirus Disease 2019 (COVID-19). Innovative approaches for evaluating the biological activity of these cytokines
Indexed as
ImmunologyTranscriptomicsVirology
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.