ArticleAnnals of gastroenterological surgery2020
Proposal of a modified subclassification system for stage III colorectal cancer: A multi-institutional retrospective analysis.
Article in Annals of gastroenterological surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed.
- Evaluating the survival benefit of adjuvant chemotherapy based on tumor deposit status in stage II colon cancer patients from SEER database.Discover oncology · 2025Article
- Impact of perioperative prognostic nutritional index changes on the survival of patients with stage II/III colorectal cancer.Annals of gastroenterological surgery · 2024Article
- Tumor deposits in colorectal cancer: Refining their definition in the TNM system.Annals of gastroenterological surgery · 2023Review
- Proposal of a modified subclassification system for stage III colorectal cancer: A multi-institutional retrospective analysis.Annals of gastroenterological surgery · 2020Article
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9 authors.
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Abstract
aimThe prognostic value of the stage III subclassification system based on the Japanese Classification of Colorectal, Appendiceal, and Anal Carcinoma has not yet been clarified. This study aimed to develop a modified system with optimal risk stratification and compare its performance with the current staging systems.
methodsClinicopathological data from 6855 patients with stage III colorectal cancers who underwent D3 dissection were collected from a nationwide multicenter database. After determining patient survival rates across 13 divisions based on pathological N stage (N1, N2a, and N2b/N3) and tumor depth (T1, T2, T3, T4a, and T4b), except for T1N2a and T1N2b/N3 due to the small number, we categorized patients into three groups and developed a trisection staging system according to the Akaike information criterion. We then compared the Akaike information criterion of the developed system with those of the current staging systems.
resultsThe T1N1
conclusionThe proposed modified system may be useful in the risk stratification of patients with stage III colorectal cancer who had undergone D3 dissection.
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