Evidence map›Paper›PMID 33318970›Full record

ArticleEuropean journal of radiology open2020

Influenza H1N1 virus-associated pneumonia often resembles rapidly progressive interstitial lung disease seen in collagen vascular diseases and COVID-19 pneumonia; CT-pathologic correlation in 24 patients.

Makiko Murota, Takeshi Johkoh, Kyung Soo Lee, Tomas Franquet, Yasuhiro Kondoh, Yoshihiro Nishiyama, Tomonori Tanaka, Hiromitsu Sumikawa, Ryoko Egashira, Norihiko Yamaguchi and 3 more

Abstract read
In one paragraph

Article in European journal of radiology open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Vaccinations in patients with interstitial lung diseases: a narrative review.European respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Special Issue: Chest Imaging 2021.European journal of radiology open · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Makiko MurotaDepartment of Radiology, Faculty of Medicine, Kagawa University, Kagawa, Japan.
Takeshi JohkohDepartment of Radiology, Kansai Rosai Hospital, Hyogo, Japan.
Kyung Soo LeeDepartment of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Tomas FranquetDepartment of Radiology, Hospital de Sant Pau, Universidad Autónoma de Barcelona, Barcelona, Spain.
Yasuhiro KondohDepartment of Respiratory and Allergic Medicine, Tosei General Hospital, Aichi, Japan.
Yoshihiro NishiyamaDepartment of Radiology, Faculty of Medicine, Kagawa University, Kagawa, Japan.
Tomonori TanakaDepartment of Pathology, Kindai University Faculty of Medicine, Osaka, Japan.
Hiromitsu SumikawaDepartment of Radiology, Sakai City Medical Center, Osaka, Japan.
Ryoko EgashiraDepartment of Radiology, Faculty of Medicine, Saga University, Saga, Japan.
Norihiko YamaguchiDepartment of Respiratory Medicine, Kinki Central Hospital of Mutual Aid Association of Public School Teachers, Hyogo, Japan.
Kiminori FujimotoDepartment of Radiology, Kurume University School of Medicine, Fukuoka, Japan.
Junya FukuokaDepartment of Laboratory of Pathology, Nagasaki University Hospital, Nagasaki, Japan.
Group of Creation of Radiological Paper from Japan in diffuse lung disease

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo describe computed tomography (CT) findings of influenza H1N1 virus-associated pneumonia (IH1N1VAP), and to correlate CT findings to pathological ones.

methodsThe study included 24 patients with IH1N1VAP. Two observers independently evaluated the presence, distribution, and extent of CT findings. CT features were divided into either classical form (C-form) or non-classical form (NC-form). C-form included: A.) broncho-bronchiolitis and bronchopneumonia type, whereas NC-forms included: B.) diffuse peribronchovascular type, simulating subacute rheumatoid arthritis-associated (RA) interstitial lung disease (ILD) and C.) lower peripheral and/or peribronchovascular type, resembling dermatomyositis-associated ILD and COVID-19 pneumonia. In 10 cases with IH1N1VAP where lung biopsy was performed, CT and pathology findings were correlated.

resultsThe most common CT findings were ground-glass opacities (24/24, 100 %) and airspace consolidation (23/24, 96 %). C-form was found in 11 (46 %) patients while NC-form in 13 (54 %). Types A, B, and C were seen in 11(46 %), 4 (17 %), and 9 (38 %) patients, respectively. The lung biopsy revealed organizing pneumonia in all patients and 6 patients (60 %) showed incorporated type organizing pneumonia that was common histological findings of rapidly progressive ILD.

conclusionIn almost half of patients of IH1N1VAP, CT images show NC-form pneumonia pattern resembling either acute or subacute RA or dermatomyositis-associated ILD and COVID-19 pneumonia.

Indexed as

Computed tomographyCOVID-19Influenza A (H1N1) virusMyositis and muscle diseasePneumoniaRheumatoid arthritis

Identifiers

PMID33318970
PMCPMC7724381

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