Evidence map›Paper›PMID 33318931›Full record

ArticleMolecular genetics and metabolism reports2020

Georgios C Kaiafas, Dionysia Papagiannopoulou, Αndroulla N Miliotou, Anastasia S Tsingotjidou, Parthenopi C Chalkidou, Aikaterini C Tsika, George A Spyroulias, Asterios S Tsiftsoglou, Lefkothea C Papadopoulou

Open access · goldAbstract read
In one paragraph

Article in Molecular genetics and metabolism reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.8field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Georgios C KaiafasLaboratory of Pharmacology, School of Pharmacy, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki 54124, Macedonia, Greece.
Dionysia PapagiannopoulouLaboratory of Medicinal Chemistry, School of Pharmacy, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki 54124, Macedonia, Greece.
Αndroulla N MiliotouLaboratory of Pharmacology, School of Pharmacy, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki 54124, Macedonia, Greece.
Anastasia S TsingotjidouLaboratory of Anatomy, Histology and Embryology, School of Veterinary Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Greece.
Parthenopi C ChalkidouLaboratory of Pharmacology, School of Pharmacy, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki 54124, Macedonia, Greece.
Aikaterini C TsikaDepartment of Pharmacy, University of Patras, 26504 Patras, Greece.
George A SpyrouliasDepartment of Pharmacy, University of Patras, 26504 Patras, Greece.
Asterios S TsiftsoglouLaboratory of Pharmacology, School of Pharmacy, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki 54124, Macedonia, Greece.
Lefkothea C PapadopoulouLaboratory of Pharmacology, School of Pharmacy, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki 54124, Macedonia, Greece.
Aristotle University of Thessaloniki · GRUniversity of Patras · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The rapid progress achieved in the development of many biopharmaceuticals had a tremendous impact on the therapy of many metabolic/genetic disorders. This type of fruitful approach, called protein replacement therapy (PRT), aimed to either replace the deficient or malfunctional protein in human tissues that act either in plasma membrane or

Indexed as

99mTc, Technetium-99 m.BSA, Bovine Serum Albumin;COX, Cytochrome c oxidase;FBS, Fetal bovine serum;IBs, Inclusion bodies;ID, Injected dose;i.p., Intraperitoneal;i.v., Intravenous;l-Arg, l-Arginine;PBS, Phosphate buffered saline;p.i., Post-injection;PRT, Protein Replacement Therapy;PTD, Protein Transduction Domain;RA, Radioactivity;RT, Room Temperature;SD, Standard Deviation;SEC, Size Exclusion Chromatography;TAT-L-Sco2, 10xHis-XaSITE-TAT-L-Sco2-HA;

Identifiers

PMID33318931
PMCPMC7726716
OpenAlexW3112054237

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.