ReviewJournal of advanced research2021
Structure-activity relationships study of isothiocyanates for H
Review in Journal of advanced research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed.
- Dietary isothiocyanates as redox-active bioactives: A comprehensive review of chemistry.Food chemistry. Molecular sciences · 2026Review
- The Complexity of Drug Development: Translational Value and Limitations of Computational ADMET Assays Applied to Approved Anticancer Drugs.Pharmaceuticals (Basel, Switzerland) · 2026Article
- Targeting oxidative stress-MMP-2 signaling in hypertension-induced cardiovascular remodeling and dysfunction.Frontiers in pharmacology · 2026Review
- Pharmacological Investigation of a Novel Resveratrol-like SIRT1 Activator Endowed with a Cardioprotective Profile.Molecules (Basel, Switzerland) · 2025Article
- Transsulfuration Pathway Products and HInternational journal of molecular sciences · 2025Review
- The Effect of the Glucosinolate Sinigrin on Alterations in Molecular Biomarkers of the Myocardium in Swiss Mice.Foods (Basel, Switzerland) · 2025Article
- Pills of Multi-Target HInternational journal of molecular sciences · 2024Review
- Erucin Exerts Cardioprotective Effects on Ischemia/Reperfusion Injury through the Modulation of mitoKATP Channels.Biomedicines · 2023Article
- Anti-Proliferative Properties of the Novel Hybrid Drug Met-ITC, Composed of the Native Drug Metformin with the Addition of an Isothiocyanate HInternational journal of molecular sciences · 2023Article
- Plants and Mushrooms as Possible New Sources of HInternational journal of molecular sciences · 2023Review
- HAntioxidants (Basel, Switzerland) · 2023Review
- Comparative Study of Different HAntioxidants (Basel, Switzerland) · 2023Article
- Prednisone-hydrogen sulfide releasing hybrid shows improved therapeutic profile in asthma.Frontiers in pharmacology · 2023Article
- Design, Synthesis and Evaluation of Novel Molecular Hybrids between Antiglaucoma Drugs and HInternational journal of molecular sciences · 2022Article
- Potential Effects of Natural HBiomolecules · 2022Review
- Beneficial Health Effects of Glucosinolates-Derived Isothiocyanates on Cardiovascular and Neurodegenerative Diseases.Molecules (Basel, Switzerland) · 2022Review
- HJournal of advanced research · 2022Article
- The Anti-Tumoral Potential of Phosphonate Analog of Sulforaphane in Zebrafish Xenograft Model.Cells · 2021Article
- The HAntioxidants (Basel, Switzerland) · 2021Article
- Modulation of EndMT by Hydrogen Sulfide in the Prevention of Cardiovascular Fibrosis.Antioxidants (Basel, Switzerland) · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe gasotransmitter hydrogen sulphide (H
methodsA library of forty-five isothiocyanates, selected for their different chemical properties, has been evaluated for its hydrogen sulfide (H
resultsThe results herein obtained strongly indicate 3-pyridyl-isothiocyanate (25) as a suitable pharmacological option in anti-ischemic therapy. The cardioprotective effects of compound 25 were tested in vivo and found to exhibit a positive effect.
conclusionResults strongly suggest that isothiocyanate-based H
Indexed as
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.