Evidence map›Paper›PMID 33318782›Full record

ArticleMelanoma management2020

Prognostic value of intratumoral lymphocyte-to-monocyte ratio and M0 macrophage enrichment in tumor immune microenvironment of melanoma.

Neil K Jairath, Mark W Farha, Ruple Jairath, Paul W Harms, Lam C Tsoi, Trilokraj Tejasvi

Abstract read
In one paragraph

Article in Melanoma management, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Integrative analysis of SEC13: a prognostic predictor and immunotherapeutic target.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. World journal of gastroenterology · 2021
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Neil K JairathDepartment of Dermatology, University of Michigan, Ann Arbor, MI 48109, USA.ORCID https://orcid.org/0000-0003-2317-169X
Mark W FarhaDepartment of Dermatology, University of Michigan, Ann Arbor, MI 48109, USA.ORCID https://orcid.org/0000-0001-8974-0184
Ruple JairathDepartment of Dermatology, University of Michigan, Ann Arbor, MI 48109, USA.ORCID https://orcid.org/0000-0002-1896-5295
Paul W HarmsDepartment of Dermatology, University of Michigan, Ann Arbor, MI 48109, USA.ORCID https://orcid.org/0000-0002-0802-2883
Lam C TsoiDepartment of Computational Medicine & Bioinformatics, Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA.ORCID https://orcid.org/0000-0003-1627-5722
Trilokraj TejasviDepartment of Dermatology, University of Michigan, Ann Arbor, MI 48109, USA.

Funding

SHORT-TERM TRAINING IN HEALTH PROF SCHOOLST35HL007690 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI FLAHERTY, KEVIN R · 1990 to 2024
$3.3M
NHLBI NIH HHS T35 HL007690
6 · The paper itself

Abstract

Skin cutaneous melanoma is characterized by significant heterogeneity in its molecular, genomic and immunologic features. Whole transcriptome RNA sequencing data from The Cancer Genome Atlas of skin cutaneous melanoma (n = 328) was utilized. CIBERSORT was used to identify immune cell type composition, on which unsupervised hierarchical clustering was performed. Analysis of overall survival was performed using Kaplan-Meier estimates and multivariate Cox regression analyses. Membership in the lymphocyte:monocyte

Indexed as

cutaneous melanomaimmunotherapylymphocytesmacrophagesmonocytesRNA sequencingtumor immune microenvironment

Identifiers

PMID33318782
PMCPMC7727784

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.