ArticleNature neuroscience2021
Microglial G
Open access · greenAbstract read
In one paragraph
Article in Nature neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
85citing papers in PubMed, 2 pooled it
7.8field-weighted citation impact, top 2% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
85 citing papers in PubMed, 2 syntheses or guidelines pooled it, 152 citations in OpenAlex.
- Cortical excitability and plasticity in Alzheimer's disease and mild cognitive impairment: A systematic review and meta-analysis of transcranial magnetic stimulation studies.Ageing research reviews · 2022Pooled it
- The Amyloid-β Pathway in Alzheimer's Disease.Molecular psychiatry · 2021Pooled it
- Sex-specific role of microglia in ΔNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- cGAS-mediated type I IFN signaling contributes to disease progression in drug-refractory epilepsy.Nature neuroscience · 2026Article
- Immune-mediated excitotoxicity in brain disorders.Nature reviews. Immunology · 2026Review
- Activity-dependent protein synthesis in neurons requires microglial-metabolic coupling.Cell metabolism · 2026Article
- Article
- Research Progress on the Biological Function and Homeostatic Disruption of Microglia in the Pathogenesis of Major Depressive Disorder.Neuroscience bulletin · 2026Review
- The axon initial segment-associated microglia regulate neuronal activity and visual perception.Cell research · 2026Article
- Microglia Modulate Information Processing in the Mouse Barrel Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Microglia surveillance is directed toward neuron activation during sustained intracortical microstimulation.Journal of neural engineering · 2026Article
- HMC3 revealed: how much do these "Microglia" really tell us?Frontiers in immunology · 2026Review
- Microglial colonization of the developing mouse brain is controlled by both microglial and neural CSF-1.The EMBO journal · 2026Article
- The metabolic engine of cognition: microglia-neuron interactions in health, ageing and disease.Nature metabolism · 2025Review
- Selective agonism of GPR34 stimulates microglial uptake and clearance of amyloid β fibrils.Alzheimer's research & therapy · 2025Article
- Adenosine in the Brain: Recent Progress on Detection, Function, and Translation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Review
- Microglia coordinate activity-dependent protein synthesis in neurons through metabolic coupling.bioRxiv : the preprint server for biology · 2025Article
- Potential roles for microglia in drug addiction: Adolescent neurodevelopment and beyond.Journal of neuroimmunology · 2025Review
- The role of electroencephalography in epilepsy research-From seizures to interictal activity and comorbidities.Epilepsia · 2025Review
- Research developments in the neurovascular unit and the blood‑brain barrier (Review).Biomedical reports · 2025Review
25 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
24 authors at 3 institutions in 1 country.
Mario Merlini *Gladstone Institutes, San Francisco, CA, USA.
Victoria A Rafalski *Gladstone Institutes, San Francisco, CA, USA.
Keran MaGladstone Institutes, San Francisco, CA, USA.
Keun-Young KimDepartment of Neurosciences, University of California, San Diego, La Jolla, CA, USA.
Eric A BushongDepartment of Neurosciences, University of California, San Diego, La Jolla, CA, USA.ORCID http://orcid.org/0000-0001-6195-2433
Pamela E Rios CoronadoGladstone Institutes, San Francisco, CA, USA.
Zhaoqi YanGladstone Institutes, San Francisco, CA, USA.
Andrew S MendiolaGladstone Institutes, San Francisco, CA, USA.ORCID http://orcid.org/0000-0002-2897-3299
Elif G SozmenGladstone Institutes, San Francisco, CA, USA.
Jae Kyu RyuGladstone Institutes, San Francisco, CA, USA.ORCID http://orcid.org/0000-0002-3992-4011
Matthias G HaberlDepartment of Neurosciences, University of California, San Diego, La Jolla, CA, USA.ORCID http://orcid.org/0000-0002-4961-7832
Matthew MadanyDepartment of Neurosciences, University of California, San Diego, La Jolla, CA, USA.
Daniel Naranjo SampsonDepartment of Neurosciences, University of California, San Diego, La Jolla, CA, USA.
Mark A PetersenGladstone Institutes, San Francisco, CA, USA.ORCID http://orcid.org/0000-0003-1366-1353
Sophia BardehleGladstone Institutes, San Francisco, CA, USA.
Reshmi TognattaGladstone Institutes, San Francisco, CA, USA.
Terry DeanGladstone Institutes, San Francisco, CA, USA.
Rosa Meza AcevedoGladstone Institutes, San Francisco, CA, USA.
Belinda CabrigaGladstone Institutes, San Francisco, CA, USA.
Reuben ThomasGladstone Institutes, San Francisco, CA, USA.
Shaun R CoughlinCardiovascular Research Institute, University of California, San Francisco, San Francisco, CA, USA.
Mark H EllismanDepartment of Neurosciences, University of California, San Diego, La Jolla, CA, USA.
Jorge J PalopGladstone Institutes, San Francisco, CA, USA.
Katerina AkassoglouGladstone Institutes, San Francisco, CA, USA. kakassoglou@gladstone.ucsf.edu.ORCID http://orcid.org/0000-0002-2632-1465
Gladstone Institutes · USUniversity of California San Diego · USUniversity of California, San Francisco · US
Funding
Neurovascular Interactions: Mechanisms, imaging, therapeutic potentialR35NS097976 · NINDS · J. DAVID GLADSTONE INSTITUTES · PI AKASSOGLOU, KATERINA · 2016 to 2023
$11.1MMOLECULAR AND CELLULAR IMMUNOLOGYT32AI007334 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CYSTER, JASON G · 1988 to 2023
$11.0MNRSA Training CoreTL1TR001871 · NCATS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KANAYA, ALKA M., SOMSOUK, MA · 2016 to 2025
$10.1MNational Center for Microscopy and Imaging Research: A BRAIN Technology Integration and Dissemination ResourceU24NS120055 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ELLISMAN, MARK H · 2021 to 2025
$5.4MFibrinogen and vascular cognitive impairment: mechanisms, imaging, therapeuticsRF1AG064926 · NIA · J. DAVID GLADSTONE INSTITUTES · PI AKASSOGLOU, KATERINA, ELLISMAN, MARK H · 2019 to 2019
$4.5MOptogenetic dissection of cellular and circuit mechanisms of network dysfunction and amyloid deposition in mouse models of Alzheimer's disease in vivoRF1AG062234 · NIA · J. DAVID GLADSTONE INSTITUTES · PI PALOP, JORGE J · 2018 to 2021
$3.8MThe National Center for Microscopy and Imaging Research, a Community-wide Scientific ResourceR24GM137200 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ELLISMAN, MARK H · 2020 to 2022
$3.0MEXTRAMULAR RESEARCH FACILITIES CONSTRUCTIONC06RR018928 · NCRR · J. DAVID GLADSTONE INSTITUTES · PI MAHLEY, ROBERT W. · 2003 to 2003
$2.1MRestoring Brain Functions in Alzheimer Models with Interneuron TransplantsR01AG047313 · NIA · J. DAVID GLADSTONE INSTITUTES · PI PALOP, JORGE J · 2014 to 2018
$1.9MFEI TITAN HALO 300kV INTERMEDIATE VOLTAGE ELECTRON MICROSCOPES10OD021784 · OD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ELLISMAN, MARK H · 2017 to 2017
$1.9MFibrinogen-mediated mechanisms of preterm infant brain injuryK02NS110973 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI PETERSEN, MARK A · 2019 to 2024
$962kFunctional Alterations of Parvalbumin Interneurons Contributing to Abnormal Network Activity in Alzheimer's Disease Mouse ModelsK99AG062776 · NIA · J. DAVID GLADSTONE INSTITUTES · PI MA, KERAN · 2019 to 2021
$393kNCATS NIH HHS TL1 TR001871NCRR NIH HHS C06 RR018928NIAID NIH HHS T32 AI007334NIA NIH HHS K99 AG062776NIA NIH HHS R01 AG047313NIA NIH HHS RF1 AG062234NIA NIH HHS RF1 AG064926NIGMS NIH HHS R24 GM137200NIH HHS S10 OD021784NINDS NIH HHS F32 NS096920NINDS NIH HHS K02 NS110973NINDS NIH HHS R35 NS097976NINDS NIH HHS U24 NS120055
Abstract
Microglial surveillance is a key feature of brain physiology and disease. Here, we found that G
Indexed as
AnimalsCalcium SignalingCell MovementConvulsantsElectroencephalographyG-Protein-Coupled Receptor Kinase 1Immunologic SurveillanceMiceMicrogliaNerve NetNervous System DiseasesNervous System Physiological PhenomenaPilocarpinerho GTP-Binding ProteinsSeizuresSignal TransductionConvulsantsG-Protein-Coupled Receptor Kinase 1Grk1 protein, mousePilocarpinerho GTP-Binding Proteins
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What OpenQuestion holds
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.