Evidence map›Paper›PMID 33318654›Full record

ArticleCommunications biology2020

Genetic ancestry, skin pigmentation, and the risk of cutaneous squamous cell carcinoma in Hispanic/Latino and non-Hispanic white populations.

Eric Jorgenson, Hélène Choquet, Jie Yin, Thomas J Hoffmann, Yambazi Banda, Mark N Kvale, Neil Risch, Catherine Schaefer, Maryam M Asgari

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Communications biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Biology · 2024
    Article
  6. Article
  7. Genetic polymorphism inSkin health and disease · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Eric JorgensonKaiser Permanente Northern California, Division of Research, Oakland, CA, 94612, USA.ORCID 0000-0002-5829-8191
Hélène ChoquetKaiser Permanente Northern California, Division of Research, Oakland, CA, 94612, USA. Helene.Choquet@kp.org.ORCID 0000-0001-9839-8667
Jie YinKaiser Permanente Northern California, Division of Research, Oakland, CA, 94612, USA.
Thomas J HoffmannInstitute for Human Genetics, UCSF, San Francisco, CA, 94143, USA.ORCID 0000-0001-6893-4449
Yambazi BandaInstitute for Human Genetics, UCSF, San Francisco, CA, 94143, USA.
Mark N KvaleInstitute for Human Genetics, UCSF, San Francisco, CA, 94143, USA.
Neil RischKaiser Permanente Northern California, Division of Research, Oakland, CA, 94612, USA.
Catherine SchaeferKaiser Permanente Northern California, Division of Research, Oakland, CA, 94612, USA.ORCID 0000-0003-2644-055X
Maryam M AsgariDepartment of Dermatology, Massachusetts General Hospital, Boston, MA, 02114, USA.ORCID 0000-0003-1582-3475
Kaiser Permanente · USHarvard University · USUniversity of California, San Francisco · US

Funding

A Resource for Genetic Epidemiology Research in Adult Health and AgingRC2AG036607 · NIA · KAISER FOUNDATION RESEARCH INSTITUTE · PI RISCH, NEIL J., SCHAEFER, CATHERINE ANN · 2009 to 2010
$24.8M
Patient-oriented research and mentoring program in dermatologic diseasesK24AR069760 · NIAMS · UNIVERSITY OF COLORADO DENVER · PI ASGARI, MARYAM MANDANA · 2017 to 2025
$1.9M
Genetic Etiology of Abdominal Hernia SusceptibilityR01DK116738 · NIDDK · KAISER FOUNDATION RESEARCH INSTITUTE · PI AHITUV, NADAV, CHOQUET, HELENE · 2018 to 2020
$1.8M
The Role of Genetic Risk Factors in Keratinocyte Carcinoma SusceptibilityR01CA241623 · NCI · KAISER FOUNDATION RESEARCH INSTITUTE · PI ASGARI, MARYAM MANDANA, CHOQUET, HELENE · 2020 to 2025
$1.7M
The Role of Refractive Error in the Etiology of GlaucomaR01EY027004 · NEI · KAISER FOUNDATION RESEARCH INSTITUTE · PI CHOQUET, HELENE · 2017 to 2020
$1.6M
PQ3 Cutaneous squamous cell carcinoma: Integrating germline and somatic alterations that underlie tumor progressionR01CA231264 · NCI · UNIVERSITY OF COLORADO DENVER · PI ASGARI, MARYAM MANDANA · 2019 to 2023
$1.5M
Genome-wide association study of cutaneous squamous cell carincomaR01CA166672 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI ASGARI, MARYAM MANDANA · 2013 to 2016
$1.3M
NCI NIH HHS R01 CA166672NCI NIH HHS R01 CA231264NCI NIH HHS R01 CA241623NCI NIH HHS R01 CA2416323NEI NIH HHS R01 EY027004NIAMS NIH HHS K24 AR069760NIA NIH HHS RC2 AG036607NIDDK NIH HHS R01 DK116738
6 · The paper itself

Abstract

Although cutaneous squamous cell carcinoma (cSCC) is one of the most common malignancies in individuals of European ancestry, the incidence of cSCC in Hispanic/Latinos is also increasing. cSCC has both a genetic and environmental etiology. Here, we examine the role of genetic ancestry, skin pigmentation, and sun exposure in Hispanic/Latinos and non-Hispanic whites on cSCC risk. We observe an increased cSCC risk with greater European ancestry (P = 1.27 × 10

Indexed as

Genetic BackgroundSkin PigmentationAgedAged, 80 and overCarcinoma, Squamous CellComputational BiologyDisease SusceptibilityFemaleHispanic or LatinoHumansMaleMiddle AgedMolecular Sequence AnnotationPolymorphism, Single NucleotideQuantitative Trait LociRisk Assessment

Identifiers

PMID33318654
PMCPMC7736583
OpenAlexW3111515782

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.