Evidence map›Paper›PMID 33318605›Full record

Trial reportScientific reports2020

Spatial constraints and cognitive fatigue affect motor imagery of walking in people with multiple sclerosis.

Jessica Podda, Ludovico Pedullà, Margherita Monti Bragadin, Elisa Piccardo, Mario Alberto Battaglia, Giampaolo Brichetto, Marco Bove, Andrea Tacchino

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Jessica PoddaScientific Research Area, Italian Multiple Sclerosis Foundation (FISM), Genoa, Italy.
Ludovico PedullàScientific Research Area, Italian Multiple Sclerosis Foundation (FISM), Genoa, Italy.
Margherita Monti BragadinScientific Research Area, Italian Multiple Sclerosis Foundation (FISM), Genoa, Italy.
Elisa PiccardoAISM Rehabilitation Service, Italian Multiple Sclerosis Society, Genoa, Italy.
Mario Alberto BattagliaDepartment of Physiopathology, Experimental Medicine and Public Health, University of Siena, Siena, Italy.
Giampaolo BrichettoScientific Research Area, Italian Multiple Sclerosis Foundation (FISM), Genoa, Italy.
Marco BoveDepartment of Experimental Medicine, Section of Human Physiology and Centro Polifunzionale di Scienze Motorie, University of Genoa, Genoa, Italy.
Andrea TacchinoScientific Research Area, Italian Multiple Sclerosis Foundation (FISM), Genoa, Italy. andrea.tacchino@aism.it.
Associazione Italiana Sclerosi Multipla · ITUniversity of Genoa · ITUniversity of Siena · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Motor imagery (MI) is the mental simulation of an action without any overt motor execution. Interestingly, a temporal coupling between durations of real and imagined movements, i.e., the so-called isochrony principle, has been demonstrated in healthy adults. On the contrary, anisochrony has frequently been reported in elderly subjects or those with neurological disease such as Parkinson disease or multiple sclerosis (MS). Here, we tested whether people with MS (PwMS) may have impaired MI when they imagined themselves walking on paths with different widths. When required to mentally simulate a walking movement along a constrained pathway, PwMS tended to overestimate mental movement duration with respect to actual movement duration. Interestingly, in line with previous evidence, cognitive fatigue was found to play a role in the MI of PwMS. These results suggest that investigating the relationship between cognitive fatigue and MI performances could be key to shedding new light on the motor representation of PwMS and providing critical insights into effective and tailored rehabilitative treatments.

Indexed as

CognitionFatigueImaginationMultiple SclerosisWalkingAdultFemaleHumansMaleMiddle Aged

Identifiers

PMID33318605
PMCPMC7736576
OpenAlexW3112926089

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.