Evidence map›Paper›PMID 33318553›Full record

ArticleScientific reports2020

Metabolomic analysis and mass spectrometry imaging after neonatal stroke and cell therapies in mouse brains.

Emi Tanaka, Yuko Ogawa, Ritsuko Fujii, Tomomi Shimonaka, Yoshiaki Sato, Takashi Hamazaki, Tokiko Nagamura-Inoue, Haruo Shintaku, Masahiro Tsuji

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Increased fatty acid metabolism and decreased glycolysis are hallmarks of metabolic reprogramming within microglia in degenerating white matter during recovery from experimental stroke.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023
    Article
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Emi TanakaDepartment of Pediatrics, Osaka City University Graduate School of Medicine, Osaka, Japan.
Yuko OgawaInstitute of Biomedical Research and Innovation, Kobe, Japan.
Ritsuko FujiiDivision of Bioenergetics, Research Center for Artificial Photosynthesis, Osaka City University, Osaka, Japan.
Tomomi ShimonakaAnalysis Division, Research Center for Artificial Photosynthesis, Osaka City University, Osaka, Japan.
Yoshiaki SatoDivision of Neonatology, Center for Maternal-Neonatal Care, Nagoya University Hospital, Nagoya, Japan.
Takashi HamazakiDepartment of Pediatrics, Osaka City University Graduate School of Medicine, Osaka, Japan.
Tokiko Nagamura-InoueDepartment of Cell Processing and Transfusion, Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
Haruo ShintakuDepartment of Pediatrics, Osaka City University Graduate School of Medicine, Osaka, Japan.
Masahiro TsujiDepartment of Food and Nutrition, Kyoto Women's University, 35 Kitahiyoshi-cho, Imakumano, Higashiyama-ku, Kyoto, 605-8501, Japan. tsujima@kyoto-wu.ac.jp.
Osaka City University · JPFoundation for Biomedical Research and Innovation · JPNagoya University Hospital · JPNational Cerebral and Cardiovascular Center · JPThe University of Tokyo · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ischemic brain injury provokes complex, time-dependent downstream pathways that ultimately lead to cell death. We aimed to demonstrate the levels of a wide range of metabolites in brain lysates and their on-tissue distribution following neonatal stroke and cell therapies. Postnatal day 12 mice underwent middle cerebral artery occlusion (MCAO) and were administered 1 × 10

Indexed as

MetabolomicsSpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationAnimalsAnimals, NewbornBrainCarnitineDisease Models, AnimalFemaleGlutamic AcidMaleMesenchymal Stem CellsMiceStrokeCarnitineGlutamic Acid

Identifiers

PMID33318553
PMCPMC7736587
OpenAlexW3111547168

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.