Evidence map›Paper›PMID 33318504›Full record

ArticleScientific reports2020

Elucidating the regulatory mechanism of Swi1 prion in global transcription and stress responses.

Zhiqiang Du, Jeniece Regan, Elizabeth Bartom, Wei-Sheng Wu, Li Zhang, Dustin Kenneth Goncharoff, Liming Li

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. [PRIONPathogens (Basel, Switzerland) · 2022
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Zhiqiang DuDepartment of Biochemistry and Molecular Genetics, Northwestern University, Chicago, 60011, USA. z-du@northwestern.edu.
Jeniece ReganDepartment of Biochemistry and Molecular Genetics, Northwestern University, Chicago, 60011, USA.
Elizabeth BartomDepartment of Biochemistry and Molecular Genetics, Northwestern University, Chicago, 60011, USA.
Wei-Sheng WuDepartment of Electrical Engineering, National Cheng Kung University, Tainan City, 701, Taiwan.
Li ZhangDepartment of Biochemistry and Molecular Genetics, Northwestern University, Chicago, 60011, USA.
Dustin Kenneth GoncharoffDepartment of Biochemistry and Molecular Genetics, Northwestern University, Chicago, 60011, USA.
Liming LiDepartment of Biochemistry and Molecular Genetics, Northwestern University, Chicago, 60011, USA. limingli@northwestern.edu.
Northwestern University · USNational Cheng Kung University · TW

Funding

Prion-mediated protein aggregation/co-aggregation and cellular consequenceR01GM126318 · NIGMS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI DU, ZHIQIANG · 2018 to 2022
$1.6M
High Throughput Screening for Small-molecules Facilitating Prion StudyR01GM110045 · NIGMS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI LI, LIMING · 2014 to 2016
$866k
NIGMS NIH HHS R01 GM110045NIGMS NIH HHS R01 GM126318NIH HHS R01GM110045NIH HHS R01GM126318
6 · The paper itself

Abstract

Transcriptional regulators are prevalent among identified prions in Saccharomyces cerevisiae, however, it is unclear how prions affect genome-wide transcription. We show here that the prion ([SWI

Indexed as

Gene Expression Regulation, FungalOsmotic PressureTranscription, GeneticChromosomal Proteins, Non-HistoneSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsTranscription FactorsChromosomal Proteins, Non-HistoneSaccharomyces cerevisiae ProteinsSWI1 protein, S cerevisiaeTranscription Factors

Identifiers

PMID33318504
PMCPMC7736884
OpenAlexW3112174793

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.