Evidence map›Paper›PMID 33318187›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

Plant stem-cell organization and differentiation at single-cell resolution.

James W Satterlee, Josh Strable, Michael J Scanlon

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 128 papers.

0numbers the graph read from it
0cells of the map it votes in
128citing papers in PubMed
37.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

128 citing papers in PubMed, 238 citations in OpenAlex.

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  11. Cell fate acquisition at a de novo developmental boundary in the maize leaf.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  19. Nanorate sequencing reveals theProceedings of the National Academy of Sciences of the United States of America · 2025
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68 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

James W SatterleeSchool of Integrative Plant Science, Cornell University, Ithaca, NY 14853.ORCID 0000-0002-0267-4944
Josh StrableSchool of Integrative Plant Science, Cornell University, Ithaca, NY 14853.ORCID 0000-0002-0260-8285
Michael J ScanlonSchool of Integrative Plant Science, Cornell University, Ithaca, NY 14853 mjs298@cornell.edu.ORCID 0000-0003-1708-3490
Cornell University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plants maintain populations of pluripotent stem cells in shoot apical meristems (SAMs), which continuously produce new aboveground organs. We used single-cell RNA sequencing (scRNA-seq) to achieve an unbiased characterization of the transcriptional landscape of the maize shoot stem-cell niche and its differentiating cellular descendants. Stem cells housed in the SAM tip are engaged in genome integrity maintenance and exhibit a low rate of cell division, consistent with their contributions to germline and somatic cell fates. Surprisingly, we find no evidence for a canonical stem-cell organizing center subtending these cells. In addition, trajectory inference was used to trace the gene expression changes that accompany cell differentiation, revealing that ectopic expression of

Indexed as

Cell DifferentiationSingle-Cell AnalysisCell DivisionGene Expression Regulation, PlantGenome, PlantMeristemPlant LeavesPlant ProteinsStem CellsTranscription, GeneticTranscriptomeZea maysPlant Proteinscell differentiationmaizeshoot apical meristemsingle-cell transcriptomics

Identifiers

PMID33318187
PMCPMC7776995
OpenAlexW3112352932

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.