Evidence map›Paper›PMID 33318138›Full record

ArticleInfection and immunity2021

G Gasperini, R Alfini, V Arato, F Mancini, M G Aruta, P Kanvatirth, D Pickard, F Necchi, A Saul, O Rossi and 2 more

Open access · greenAbstract read
In one paragraph

Article in Infection and immunity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Review
  3. Multivalent vaccines for invasiveInfection and immunity · 2026
    Review
  4. Protein-centric mechanisms of typhoidalFrontiers in cellular and infection microbiology · 2026
    Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. Review
  13. Article
  14. Article
  15. Enterococcal Membrane Vesicles as Vaccine Candidates.International journal of molecular sciences · 2023
    Article
  16. Opportunities for engineering outer membrane vesicles using synthetic biology approaches.Extracellular vesicles and circulating nucleic acids · 2023
    Article
  17. Article
  18. Article
  19. Article
  20. Paratyphoid Fever A: Infection and Prevention.Frontiers in microbiology · 2022
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

G GasperiniGSK Vaccines institute for Global Health, Siena, Italy.
R AlfiniGSK Vaccines institute for Global Health, Siena, Italy.
V AratoGSK Vaccines institute for Global Health, Siena, Italy.
F ManciniGSK Vaccines institute for Global Health, Siena, Italy.
M G ArutaGSK Vaccines institute for Global Health, Siena, Italy.
P KanvatirthUniversity of Cambridge, Cambridge, United Kingdom.
D PickardUniversity of Cambridge, Cambridge, United Kingdom.
F NecchiGSK Vaccines institute for Global Health, Siena, Italy.
A SaulGSK Vaccines institute for Global Health, Siena, Italy.
O RossiGSK Vaccines institute for Global Health, Siena, Italy.ORCID 0000-0002-0170-1285
F Micoli *GSK Vaccines institute for Global Health, Siena, Italy francesca.x.micoli@gsk.com pm274@cam.ac.uk.
P Mastroeni *University of Cambridge, Cambridge, United Kingdom francesca.x.micoli@gsk.com pm274@cam.ac.uk.ORCID 0000-0003-3838-4962
Toscana Life Sciences · ITUniversity of Cambridge · GB

Funding

Biotechnology and Biological Sciences Research CouncilMedical Research Council MR/R005974/1
6 · The paper itself

Abstract

Typhoid and paratyphoid fevers have a high incidence worldwide and coexist in many geographical areas, especially in low-middle-income countries (LMIC) in South and Southeast Asia. There is extensive consensus on the urgent need for better and affordable vaccines against systemic

Indexed as

AnimalsAntigens, BacterialDisease Models, AnimalHumansImmunizationImmunogenicity, VaccineMiceO AntigensParatyphoid FeverPolysaccharides, BacterialSalmonella paratyphi ATransport VesiclesVaccines, CombinedAntigens, BacterialO AntigensPolysaccharides, BacterialVaccines, Combinedenteric feverGMMAOMVSalmonellaS. ParatyphiS. Typhityphoid fevervaccineVi

Identifiers

PMID33318138
PMCPMC8090967
OpenAlexW3112377963

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.