ArticleHospital pediatrics2021
Characteristics of Afebrile Infants ≤60 Days of Age With Invasive Bacterial Infections.
Article in Hospital pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 12 citations in OpenAlex.
- Prevalence of Serious Bacterial Infection in Young Infants with Hypothermia with Positive Respiratory Pathogen Testing.Journal of pediatrics. Clinical practice · 2024Article
- Article
- Biomarkers and their association with bacterial illnesses in hypothermic infants.The American journal of emergency medicine · 2023Article
- Microbiological and clinical characteristics of invasive Group B Streptococcal blood stream infections in children and adults from Qatar.BMC infectious diseases · 2022Article
- Impact of a Hypothermic Young Infant Clinical Pathway: A Single Site Study.Sage open pediatricsArticle
Corrections and comments
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Authors and funding
14 authors at 11 institutions in 1 country.
Funding
Abstract
objectivesTo describe the characteristics and outcomes of afebrile infants ≤60 days old with invasive bacterial infection (IBI).
methodsWe conducted a secondary analysis of a cross-sectional study of infants ≤60 days old with IBI presenting to the emergency departments (EDs) of 11 children's hospitals from 2011 to 2016. We classified infants as afebrile if there was absence of a temperature ≥38°C at home, at the referring clinic, or in the ED. Bacteremia and bacterial meningitis were defined as pathogenic bacterial growth from a blood and/or cerebrospinal fluid culture.
resultsOf 440 infants with IBI, 78 (18%) were afebrile. Among afebrile infants, 62 (79%) had bacteremia without meningitis and 16 (20%) had bacterial meningitis (10 with concomitant bacteremia). Five infants (6%) died, all with bacteremia. The most common pathogens were
conclusionsMost afebrile young infants with an IBI had vital sign, examination, or laboratory abnormalities. Future studies should evaluate the predictive ability of these criteria in afebrile infants undergoing evaluation for IBI.
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Registered trials
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