ArticleThe Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation2021
A novel method of donor‒recipient size matching in pediatric heart transplantation: A total cardiac volume‒predictive model.
Article in The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Impact of varying degree of donor-recipient weight mismatch on survival outcomes in pediatric heart transplantation.Indian journal of thoracic and cardiovascular surgery · 2026Article
- Deep Learning for Automated Measurement of Total Cardiac Volume for Heart Transplantation Size Matching.Pediatric cardiology · 2025Article
- Identifying Predictors of Psychological Problems Among Adolescents With Congenital Heart Disease for Referral to Psychological Care: A Pilot Study.CJC pediatric and congenital heart disease · 2023Article
- Female donor hearts can improve survival for male pediatric heart transplant recipients.Pediatric transplantation · 2023Article
- Evaluating predicted heart mass in adolescent heart transplantation.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2022Article
- Evidence supporting total cardiac volumes instead of weight for transplant size-matching.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2021Article
- Neonatal donation: are newborns too young to be recognized?European journal of pediatrics · 2021Article
- Reducing the wait: TCV can expand the donor pool for heart transplant candidates.Pediatric transplantation · 2021Article
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Authors and funding
8 authors.
Funding
Abstract
backgroundThe pediatric heart transplant community uses weight-based donor-to-recipient size matching almost exclusively, despite no evidence to validate weight as a reliable surrogate of cardiac size. Donor size mismatch is the second most common reason for the refusal of donor hearts in current practice (∼30% of all refusals). Whereas case-by-case segmentation of total cardiac volume (TCV) by computed tomography (CT) for direct virtual transplantation is an attractive option, it remains limited by the unavailability of donor chest CT. We sought to establish a predictive model for donor TCV on the basis of anthropomorphic and chest X-ray (CXR) cardiac measures.
methodsBanked imaging studies from 141 subjects with normal CT chest angiograms were obtained and segmented using 3-dimensional modeling to derive TCV. CXR data were available for 62 of those subjects. A total of 3 predictive models of TCV were fit through multiple linear regression using the following variables: Model A (weight only); Model B (weight, height, sex, and age); Model C (weight, height, sex, age, and 1-view anteroposterior CXR maximal horizontal cardiac width).
resultsModel C provided the most accurate prediction of TCV (optimism corrected R
conclusionsTCV can be predicted accurately using readily available anthropometrics and a 1-view CXR from donor candidates. This simple and scalable method of TCV estimation may provide a reliable and consistent method to improve donor size matching.
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