ArticleParasites & vectors2020
Insecticide resistance status of Aedes aegypti in Bangladesh.
Article in Parasites & vectors, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 51 citations in OpenAlex.
- Leish-F1 Multi-epitope Lentiviral Vaccine as a Novel Candidate Against Leishmania major in Balb/c Mice.Biochemical genetics · 2026Article
- Fitness compatibility and dengue virus Inhibition in a Bangladeshi strain of Aedes aegypti infected with the Wolbachia strain wAlbB.Scientific reports · 2025Article
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- Insecticide resistance status and mechanisms in Aedes aegypti and Aedes albopictus from different dengue endemic regions of Panama.Tropical medicine and health · 2024Article
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- Two decades of endemic dengue in Bangladesh (2000-2022): trends, seasonality, and impact of temperature and rainfall patterns on transmission dynamics.Journal of medical entomology · 2024Article
- An effective pan-serotype dengue vaccine and enhanced control strategies could help in reducing the severe dengue burden in Bangladesh-A perspective.Frontiers in microbiology · 2024Review
- Public knowledge, belief, and preventive practices regarding dengue: Findings from a community-based survey in rural Bangladesh.PLoS neglected tropical diseases · 2023Article
- Different mechanisms of X-ray irradiation-induced male and female sterility in Aedes aegypti.BMC biology · 2023Article
- Protein Profiling ofInternational journal of molecular sciences · 2023Article
- Insecticide resistance compromises the control of Aedes aegypti in Bangladesh.Pest management science · 2023Article
- The Potential ofJournal of fungi (Basel, Switzerland) · 2023Article
- Nontarget Analysis of Polluted Surface Waters in Bangladesh Using Open Science Workflows.Environmental science & technology · 2023Article
- Importance ofBiosafety and health · 2023Review
- Worldwide Status of Insecticide Resistance ofJournal of arthropod-borne diseases · 2023Review
- Increasing Dengue Burden and Severe Dengue Risk in Bangladesh: An Overview.Tropical medicine and infectious disease · 2023Review
- First comprehensive report of the resistance ofHeliyon · 2023Article
- Preliminary Report of the Insecticide Susceptibility Status of Aedes albopictus in Bangladesh.The American journal of tropical medicine and hygiene · 2021Article
- Management of insecticides for use in disease vector control: Lessons from six countries in Asia and the Middle East.PLoS neglected tropical diseases · 2021Article
- Dengue outbreaks in Bangladesh: Historic epidemic patterns suggest earlier mosquito control intervention in the transmission season could reduce the monthly growth factor and extent of epidemics.Current research in parasitology & vector-borne diseases · 2021Article
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10 authors at 3 institutions in 4 countries.
Funding
Abstract
backgroundArboviral diseases, including dengue and chikungunya, are major public health concerns in Bangladesh where there have been unprecedented levels of transmission reported in recent years. The primary approach to control these diseases is to control the vector Aedes aegypti using pyrethroid insecticides. Although chemical control has long been practiced, no comprehensive analysis of Ae. aegypti susceptibility to insecticides has been conducted to date. The aim of this study was to determine the insecticide resistance status of Ae. aegypti in Bangladesh and investigate the role of detoxification enzymes and altered target site sensitivity as resistance mechanisms.
methodsEggs of Aedes mosquitoes were collected using ovitraps from five districts across Bangladesh and in eight neighborhoods of the capital city Dhaka, from August to November 2017. CDC bottle bioassays were conducted for permethrin, deltamethrin, malathion, and bendiocarb using 3- to 5-day-old F
resultsHigh levels of resistance to permethrin were detected in all Ae. aegypti populations, with mortality ranging from 0 to 14.8% at the diagnostic dose. Substantial resistance continued to be detected against higher (2×) doses of permethrin (5.1-44.4% mortality). Susceptibility to deltamethrin and malathion varied between populations while complete susceptibility to bendiocarb was observed in all populations. Significantly higher levels of esterase and oxidase activity were detected in most of the test populations as compared to the susceptible reference Rockefeller strain. A significant association was detected between permethrin resistance and the presence of Gly1016 and Cys1534 homozygotes. The frequency of kdr (knockdown resistance) alleles varied across the Dhaka Aedes populations. Leu410 was not detected in any of the tested populations.
conclusionsThe detection of widespread pyrethroid resistance and multiple resistance mechanisms highlights the urgency for implementing alternate Ae. aegypti control strategies. In addition, implementing routine monitoring of insecticide resistance in Ae. aegypti in Bangladesh will lead to a greater understanding of susceptibility trends over space and time, thereby enabling the development of improved control strategies.
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