Evidence map›Paper›PMID 33317424›Full record

ArticleEmerging microbes & infections2021

A household case evidences shorter shedding of SARS-CoV-2 in naturally infected cats compared to their human owners.

Víctor Neira, Bárbara Brito, Belén Agüero, Felipe Berrios, Valentina Valdés, Alberto Gutierrez, Naomi Ariyama, Patricio Espinoza, Patricio Retamal, Edward C Holmes and 12 more

Abstract read
In one paragraph

Article in Emerging microbes & infections, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed.

  1. Article
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  5. Review
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  9. Article
  10. Assessing the Potential Role of Cats (Pathogens (Basel, Switzerland) · 2023
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. SARS-CoV-2 Seroprevalence Studies in Pets, Spain.Emerging infectious diseases · 2023
    Article
  19. Article
  20. Article

8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Víctor NeiraFacultad de Ciencias Veterinarias y Pecuarias, Departamento de Medicina Preventiva, Universidad de Chile, Santiago, Chile.
Bárbara BritoThe three institute - University of Technology Sydney, Sydney, Australia.
Belén AgüeroFacultad de Ciencias Veterinarias y Pecuarias, Departamento de Medicina Preventiva, Universidad de Chile, Santiago, Chile.
Felipe BerriosFacultad de Ciencias Veterinarias y Pecuarias, Departamento de Medicina Preventiva, Universidad de Chile, Santiago, Chile.
Valentina ValdésFacultad de Ciencias Veterinarias y Pecuarias, Departamento de Medicina Preventiva, Universidad de Chile, Santiago, Chile.
Alberto GutierrezFacultad de Ciencias Veterinarias y Pecuarias, Departamento de Medicina Preventiva, Universidad de Chile, Santiago, Chile.
Naomi AriyamaFacultad de Ciencias Veterinarias y Pecuarias, Departamento de Medicina Preventiva, Universidad de Chile, Santiago, Chile.ORCID https://orcid.org/0000-0002-4713-5979
Patricio EspinozaFacultad de Ciencias Veterinarias y Pecuarias, Departamento de Medicina Preventiva, Universidad de Chile, Santiago, Chile.
Patricio RetamalFacultad de Ciencias Veterinarias y Pecuarias, Departamento de Medicina Preventiva, Universidad de Chile, Santiago, Chile.
Edward C HolmesSchool of Life and Environmental Sciences and School of Medical Sciences, Marie Bashir Institute for Infectious Diseases and Biosecurity, The University of Sydney, Sydney, Australia.
Ana S Gonzalez-ReicheDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Zenab KhanDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Adriana van de GuchteDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Jayeeta DuttaDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Lisa MiorinDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Thomas KehrerDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Nicolás GalarceFacultad de Ciencias Veterinarias y Pecuarias, Departamento de Medicina Preventiva, Universidad de Chile, Santiago, Chile.
Leonardo I AlmonacidDepartamento de Enfermedades Infecciosas e Inmunología Pediátrica, Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
Jorge LevicanDepartamento de Enfermedades Infecciosas e Inmunología Pediátrica, Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
Harm van BakelDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Adolfo García-SastreDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Rafael A MedinaDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Funding

Big Omics Data Engine 2 SupercomputerS10OD026880 · OD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KOVATCH, PATRICIA · 2019 to 2019
$2.0M
Transforming Genomics with 5 PB Big Omics Data Engine Cray CS300-AC SupercomputerS10OD018522 · OD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KOVATCH, PATRICIA · 2014 to 2014
$1.9M
NIAID NIH HHS HHSN272201400008CNIH HHS S10 OD018522NIH HHS S10 OD026880
6 · The paper itself

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been detected in domestic and wild cats. However, little is known about natural viral infections of domestic cats, although their importance for modelling disease spread, informing strategies for managing positive human-animal relationships and disease prevention. Here, we describe the SARS-CoV-2 infection in a household of two human adults and sibling cats (one male and two females) using real-time RT-PCR, an ELISA test, viral sequencing, and virus isolation. On May 5th, 2020, the cat-owners tested positive for SARS-CoV-2. Two days later, the male cat showed mild respiratory symptoms and tested positive. Four days after the male cat, the two female cats became positive, asymptomatically. Also, one human and one cat showed antibodies against SARS-CoV-2. All cats excreted detectable SARS-CoV-2 RNA for a shorter duration than humans and viral sequences analysis confirmed human-to-cat transmission. We could not determine if cat-to-cat transmission also occurred.

Indexed as

Virus SheddingAdultAnimalsCatsChileCOVID-19FemaleGenome, ViralHumansMaleMiddle AgedRNA, ViralSARS-CoV-2RNA, Viraldomestic catshouseholdsnatural infectionSARS-CoV-2viral shedding

Identifiers

PMID33317424
PMCPMC7939552

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.