ArticleThe Journal of international medical research2020
Efficacy of different interventions for the treatment of postherpetic neuralgia: a Bayesian network meta-analysis.
Article in The Journal of international medical research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.
- Botulinum Toxin Type A for Trigeminal and Postherpetic Neuralgia: An Umbrella Review of Systematic Reviews.Drugs · 2026Pooled it
- Clinical research on traditional Chinese medicine for Postherpetic neuralgia: an evidence map.Frontiers in neurology · 2025Pooled it
- Effectiveness and safety of stellate ganglion block with trioxygen autologous blood retransfusion therapy for facial postherpetic neuralgia in elderly patients.Scientific reports · 2025Trial
- Efficacy and safety of stellate ganglion block for postherpetic neuralgia: a systematic review and meta-analysis protocol.BMJ open · 2026Article
- Acupuncture-Based Interventions for Sleep Outcomes in Patients with Postherpetic Neuralgia: A Systematic Review and Meta-Analysis.Journal of pain research · 2026Review
- Efficacy of Pulsed Radiofrequency Combination Therapy for Postherpetic Neuralgia: A Systematic Review and Bayesian Network Meta-Analysis.Journal of pain research · 2026Review
- CT-Guided Dorsal Root Ganglion Pulsed Radiofrequency Alone, with Ozone, or with Platelet-Rich Plasma for Postherpetic Neuralgia: A Randomized Controlled Trial.Journal of pain research · 2026Article
- Article
- Exploring the causal relationship between plasma proteins and postherpetic neuralgia: a Mendelian randomization study.Frontiers in neurology · 2025Article
- Efficacy and safety of ozone injection into the intervertebral foramen for treating patients with chronic, intractable postherpetic neuralgia: a one-year follow-up study.Frontiers in neurology · 2025Article
- The evolving role of truncal fascial plane blocks in non-surgical pain therapy: a narrative review.Frontiers in medicine · 2025Review
- Ultrasound-Guided Selective Thoracic Nerve Root Block Combined with Continuous Erector Spinae Plane Block for Postherpetic Neuralgia: A Case Report.Local and regional anesthesia · 2025Article
- Therapeutic Strategies for Postherpetic Neuralgia: Mechanisms, Treatments, and Perspectives.Current pain and headache reports · 2023Review
- Effect of Epidural Block in the Incidence of Postherpetic Neuralgia: A Population-Based Matched-Cohort Study.Annals of geriatric medicine and research · 2023Article
- Peripheral Nerve Stimulation of the Lesser Occipital and Greater Auricular Nerve for Post Herpetic Neuralgia in a Case of Ramsay Hunt Syndrome: Case Report.Orthopedic reviews · 2023Article
- Comparison of the Efficacy of Short-term Peripheral Nerve Stimulation and Pulsed Radiofrequency for Treating Herpes Zoster Ophthalmicus Neuralgia.The Clinical journal of pain · 2022Article
- Development of a Model for Predicting the Effectiveness of Pulsed Radiofrequency on Zoster-Associated Pain.Pain and therapy · 2022Article
- Pulsed Radiofrequency Combined With Methylene Blue Paravertebral Nerve Block Effectively Treats Thoracic Postherpetic Neuralgia.Frontiers in neurology · 2022Article
- Effective Treatment of Postherpetic Neuralgia at the First Branch of the Trigeminal Nerve by High-Voltage Pulsed Radiofrequency.Frontiers in neurology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveWe aimed to perform a network meta-analysis that combined both direct and indirect evidence to compare the relative efficacy of interventional therapies to treat patients with postherpetic neuralgia (PHN) and to determine the treatments' superiority and validity.
methodA conventional paired meta-analysis was performed. This was followed by a network meta-analysis using the Bayesian framework.
resultsBotulinum toxin type A and pulsed radiofrequency (PRF) were the two most effective individual interventions. For combination therapy, PRF + nerve block (NB) was the best choice, followed by subcutaneous injection or local infiltration (SC) + NB + ozone (O3). However, the combination of PRF + NB + SC showed reduced the efficacy compared with each treatment and was highly invasive for patients. After a long-term follow-up, PRF was shown to be the most effective therapy for treating patients with PHN.
conclusionsRegular anti-neuropathic drug administration that was accompanied by interventional therapies at an early stage is the best choice to treat patients with PHN. Appropriate combinations of different interventions show improved pain relief. Clinicians should manage therapeutic regimens on the basis of the patients specific condition and existing measures and strive to achieve personalized treatment.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.