ArticleClinical and molecular hepatology2021
Association between new-onset liver cirrhosis and suicide risk in South Korea: A nationwide cohort study.
Article in Clinical and molecular hepatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 18 citations in OpenAlex.
- Suicide mortality in metabolic dysfunction-associated liver diseases: a nationwide cohort study.Annals of medicine · 2026Article
- Mediating effect of coping style between family resilience and demoralization in patients with decompensated cirrhosis.Scientific reports · 2026Article
- Impact of gastrectomy on the risk of alcohol-associated liver disease in patients with gastric cancer.Scientific reports · 2026Article
- Low-density lipoprotein cholesterol and clinical outcomes in patients with liver cirrhosis: a nationwide cohort study.Annals of medicine · 2025Article
- Lower incidence of hepatocellular carcinoma with tenofovir alafenamide in chronic hepatitis B: Evidence from a large-scale cohort.JHEP reports : innovation in hepatology · 2025Article
- Association Between Triglyceride/High-Density Lipoprotein Ratio and Incidence Risk of Heart Failure: A Population-Based Cohort Study.Journal of clinical medicine · 2025Article
- Comparative Interrupted Time Series Analysis of Medical Expenses in Patients with Intertrochanteric Fracture Who Underwent Internal Fixation and Hemiarthroplasty.Hip & pelvis · 2024Article
- Stigmatization of drinking patients with liver cancer: The role of socioeconomic status.Heliyon · 2024Article
- Comparative Interrupted Time Series Analysis of Direct Medical Expense and Length of Stay in Elderly Patients with Femoral Neck Fractures Who Underwent Total Hip Arthroplasty and Hemiarthroplasty: A Real World Nationwide Database Study.Clinics in orthopedic surgery · 2024Article
- AASLD Practice Guidance: Palliative care and symptom-based management in decompensated cirrhosis.Hepatology (Baltimore, Md.) · 2022Article
- Association between new-onset Parkinson's disease and suicide risk in South Korea: a nationwide cohort study.BMC psychiatry · 2022Article
- Development of Open-Angle Glaucoma in Adults With Seropositive Rheumatoid Arthritis in Korea.JAMA network open · 2022Article
- A need for patient-centered care in managing patients with liver cirrhosis.Clinical and molecular hepatology · 2021Article
- Association between the coronavirus disease pandemic and antipsychotic drug prescriptions among patients with dementia.Journal of Alzheimer's disease reportsArticle
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
aimsCurrent evidence suggests that liver cirrhosis (LC) causes severe psychological stress and depression, which are risk factors for suicide. Although previous studies reported the association between LC and suicidal thoughts, little is known of its effect on suicidal deaths. Therefore, this study was undertaken to investigate the effect of new-onset LC on suicide.
methodsFrom the National Health Insurance Service-National Sample Cohort of South Korea, 5,809 incident LC patients and 11,618 risk-set controls matched by propensity score were selected for follow-up. The incidence rate of suicide was estimated using a generalized estimating equation with a Poisson distribution. Effect size was presented as a hazard ratio (HR) using Cox's proportional hazards model.
resultsThe incidence rate of suicide was 143.3 cases per 100,000 person years (95% confidence interval [CI], 100.2-205.1) among the LC cohort. The LC patients were 2.37 times more likely to commit suicide compared with matched controls (HR, 2.37; 95% CI, 1.44-3.88). Increased suicide risk was evident within the first 2 years of the follow-up period (HR, 2.59; 95% CI, 1.20-5.60) and among the 18-49-year-old age group (HR, 3.72; 95% CI, 1.45-9.56).
conclusionOur study found increased risk of suicide in patients with new onset LC, especially during the early period following diagnosis and in younger patients. To decrease this suicide risk, a regular and continuous social support system is required.
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