ArticleJournal of bone metabolism2020
The 2nd Metacarpal Cortical Index as a Simple Screening Tool for Osteopenia.
Article in Journal of bone metabolism, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- A Biomechanical Analysis of Intramedullary Threaded Nail Fixation and Dorsal Plate and Screw Fixation for Metacarpal Base Fractures.Journal of hand surgery global online · 2027Article
- Cortical indices, DXA, and FRAX as indicators of bone fragility: a comparative human cadaveric study.JBMR plus · 2026Article
- Rethinking Lafontaine Criteria: Second Metacarpal Cortical Percentage as a Reliable Predictor of Distal Radius Fracture Instability.Hand (New York, N.Y.) · 2026Article
- The Swiss Cheese Effect: A Biomechanical Study of Fifth Metacarpal Structural Integrity After Multiple Kirschner Wire Passes.Journal of hand surgery global online · 2026Article
- Intramedullary Threaded Nail Versus Dorsal Plate and Screw Fixation of Comminuted Metacarpal Shaft Fractures: A Cadaveric Biomechanical Study.Journal of hand surgery global online · 2026Article
- Deltoid Tuberosity Index as a Predictor of Hip Fracture Risk in Older Adults.Geriatric orthopaedic surgery & rehabilitation · 2026Article
- Assessment of Bone Density in Osteogenesis Imperfecta in Pediatric and Adolescent Age Group: Can the Metacarpal Index Play a Role?Indian journal of orthopaedics · 2025Article
- Osteoporosis prediction from hand X-ray images using segmentation-for-classification and self-supervised learning.Scientific reports · 2025Article
- Metacarpal cortical percentage predicts bone density and osteoporotic fracture incidence in inflammatory arthropathy patients: a retrospective cohort study.Archives of osteoporosis · 2025Article
- Bone Health, Fragility Fractures, and the Hand Surgeon.Journal of hand surgery global online · 2025Review
- Gender and age differences in the associations between cortical thickness and hand osteoarthritis severity: data from the Osteoarthritis Initiative.Osteoarthritis and cartilage · 2024Observational
- The Orthopedic Upper Extremity Surgeon's Role in the Diagnosis and Treatment of Osteoporosis: Making Use of Opportunistic Imaging.Journal of clinical medicine · 2024Review
- Opportunistic hand radiographs to screen for low forearm bone mineral density: a prospective and retrospective cohort study.BMC musculoskeletal disorders · 2024Article
- A Healed Intertrochanteric Femur Fracture, Shoulder, and Rib Fractures in an Ancient Nubian Female: An Osteoarchaeological Perspective.TheScientificWorldJournal · 2024Article
- Development of Osteopenia During Distal Radius Fracture Recovery.Journal of hand surgery global online · 2022Article
- Sex and External Size Specific Limitations in Assessing Bone Health From Adult Hand Radiographs.JBMR plus · 2022Article
- Machine Learning for Opportunistic Screening for Osteoporosis from CT Scans of the Wrist and Forearm.Diagnostics (Basel, Switzerland) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOsteopenia is a known risk factor for sustaining skeletal fractures. Prevention of fragility fractures has obvious clinical and economic advantages, however screening all patients using a dual energy X-ray absorptiometry (DXA) is controversial not only because of the cost implications but also because it would potentially involve exposing a percentage of normal patients to unnecessary radiation. We wished to assess whether a simple hand X-ray measuring the 2nd metacarpal cortical index (2MCI) could be used as a simple screening tool for identifying patients with osteopenia.
methodsWe retrospectively collected the radiographic data of 206 patients who had a simple radiograph of the hand and a DXA scan within one year of each other from our picture archiving and communication system database. The 2MCI was calculated for all patients. As data was parametric, a Pearson's correlation was performed to assess association between Tscores and 2MCI. Further analysis involved the construction of receiver operating characteristic (ROC) curves to identify a 2MCI index, which would give the most appropriate sensitivity and specificity values for identifying the presence of osteopenia.
resultsA statistically significant and moderate correlation between DXA T-scores and 2MCI values was found (r=0.54, n=206, P<0.001). Further ROC curve analysis of normal and osteopenic subjects identified that a 2MCI of 41.5 had a sensitivity of 100% and specificity of 53% for detecting osteopenia.
conclusionsOur results support the use of the 2MCI as a simple screening tool for identifying patients with osteopenia.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.