Evidence map›Paper›PMID 33317156›Full record

Trial reportNutrients2020

Selenium and Coenzyme Q10 Supplementation Improves Renal Function in Elderly Deficient in Selenium: Observational Results and Results from a Subgroup Analysis of a Prospective Randomised Double-Blind Placebo-Controlled Trial.

Urban Alehagen, Jan Aaseth, Jan Alexander, Kerstin Brismar, Anders Larsson

Open access · goldAbstract readObservational StudyRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 2 countries.

Urban AlehagenDivision of Cardiovascular Medicine, Department of Health, Medicine and Caring Sciences, Linköping University, SE-581 85 Linköping, Sweden.
Jan AasethResearch Department, Innlandet Hospital Trust, N-2381 Brumunddal, Norway.ORCID 0000-0002-7518-5703
Jan AlexanderNorwegian Institute of Public Health, N-0403 Oslo, Norway.ORCID 0000-0002-6381-5720
Kerstin BrismarDepartment of Molecular Medicine and Surgery, Karolinska University Hospital, Karolinska Institutet, SE-17176 Stockholm, Sweden.
Anders LarssonDepartment of Medical Sciences, Uppsala University, SE-751 85 Uppsala, Sweden.ORCID 0000-0003-3161-0402
Innlandet Hospital Trust · NOKarolinska University Hospital · SELinköping University · SENorwegian Institute of Public Health · NOUppsala University · SE

Funding

PharmaNord APS, Velje, Denmark, County Council of Östergötland, Sweden not applicable
6 · The paper itself

Abstract

A low selenium intake is found in European countries, and is associated with increased cardiovascular mortality. There is an association between selenium level and the severity of kidney disease. An association between inflammation and selenium intake is also reported. The coenzyme Q10 level is decreased in kidney disease. The aim of this study was to examine a possible association between selenium and renal function in an elderly population low in selenium and coenzyme Q

Indexed as

Dietary SupplementsAgedAged, 80 and overAntioxidantsDouble-Blind MethodFemaleGeriatric AssessmentHumansKidneyMaleProspective StudiesSeleniumSwedenUbiquinoneVitaminsAntioxidantscoenzyme Q10SeleniumUbiquinoneVitaminscardiovascular mortalitycoenzyme Q10elderlymicronutrientsrenal functionseleniumsupplementation

Identifiers

PMID33317156
PMCPMC7764721
OpenAlexW3111554851

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.