Evidence map›Paper›PMID 33317121›Full record

ArticleInternational journal of environmental research and public health2020

Predictors of Plasma Fluoride Concentrations in Children and Adolescents.

Jenny L Carwile, Katherine A Ahrens, Shravanthi M Seshasayee, Bruce Lanphear, Abby F Fleisch

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Urinary Fluoride Levels among Canadians with and without Community Water Fluoridation.International journal of environmental research and public health · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Jenny L CarwileCenter for Outcomes Research and Evaluation, Maine Medical Center Research Institute, Portland, ME 04101, USA.ORCID 0000-0002-7229-5712
Katherine A AhrensMuskie School of Public Service, University of Southern Maine, Portland, ME 04101, USA.ORCID 0000-0001-5139-9208
Shravanthi M SeshasayeeCenter for Outcomes Research and Evaluation, Maine Medical Center Research Institute, Portland, ME 04101, USA.
Bruce LanphearFaculty of Health Sciences, Simon Fraser University, Vancouver, BC V5A 1S6, Canada.
Abby F FleischCenter for Outcomes Research and Evaluation, Maine Medical Center Research Institute, Portland, ME 04101, USA.
Maine Medical Center · USMaine Medical Center · USSimon Fraser University · CAUniversity of Southern Maine · US

Funding

Prospective associations of childhood PFAS with metabolomic profiles, pubertal timing, and bone healthR01ES030101 · NIEHS · MAINEHEALTH · PI Abby Fleisch · 2019 to 2026
$3.6M
Air Pollution Exposure during Pregnancy, Maternal Glycemia, and OffspringGrowthK23ES024803 · NIEHS · MAINEHEALTH · PI FLEISCH, ABBY · 2015 to 2019
$835k
NIEHS NIH HHS K23ES024803NIEHS NIH HHS R01ES030101
6 · The paper itself

Abstract

Despite increasing concerns about neurotoxicity of fluoride in children, sources of fluoride exposure apart from municipal water fluoridation are poorly understood. We aimed to describe the associations of demographics, drinking water characteristics, diet, and oral health behaviors with plasma fluoride concentrations in U.S. children. We used data from 3928 6-19-year-olds from the 2013-2016 National Health and Nutrition Examination Survey. We used a 24-h dietary recall to estimate recent consumption of fluoridated tap water and select foods. We estimated the associations of fluoridated tap water, time of last dental visit, use of toothpaste, and frequency of daily tooth brushing with plasma fluoride concentrations. The participants who consumed fluoridated (≥0.7 mg/L) tap water (n = 560, 16%) versus those who did not had 36% (95% CI: 22, 51) higher plasma fluoride. Children who drank black or green tea (n = 503, 13%) had 42% higher plasma fluoride concentrations (95% CI: 27, 58) than non-tea drinkers. The intake of other foods and oral health behaviors were not associated with plasma fluoride concentrations. The consumption of fluoridated tap water and tea substantially increases plasma fluoride concentrations in children. Quantifying the contribution of diet and other sources of fluoride is critical to establishing safe target levels for municipal water fluoridation.

Indexed as

FluoridesNutrition SurveysAdolescentAdultChildEatingFemaleFluoridationHumansMalePlasmaYoung AdultFluorideschildrenfluorideNational Health and Nutrition Examination SurveyteawaterWhat We Eat in America

Identifiers

PMID33317121
PMCPMC7764416
OpenAlexW3112547900

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.