Evidence map›Paper›PMID 33317114›Full record

ArticleAnimals : an open access journal from MDPI2020

Surveillance Study of Hepatitis E Virus (HEV) in Domestic and Wild Ruminants in Northwestern Italy.

Andrea Palombieri, Serena Robetto, Federica Di Profio, Vittorio Sarchese, Paola Fruci, Maria Cristina Bona, Giuseppe Ru, Riccardo Orusa, Fulvio Marsilio, Vito Martella and 1 more

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Andrea PalombieriFaculty of Veterinary Medicine, Università degli Studi di Teramo, 64100 Teramo TE, Italy.
Serena RobettoIstituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d'Aosta (IZS PLV), 11020 Quart AO, Italy.
Federica Di ProfioFaculty of Veterinary Medicine, Università degli Studi di Teramo, 64100 Teramo TE, Italy.
Vittorio SarcheseFaculty of Veterinary Medicine, Università degli Studi di Teramo, 64100 Teramo TE, Italy.
Paola FruciFaculty of Veterinary Medicine, Università degli Studi di Teramo, 64100 Teramo TE, Italy.ORCID 0000-0002-6946-8467
Maria Cristina BonaIstituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d'Aosta (IZS PLV), 11020 Quart AO, Italy.
Giuseppe RuIstituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d'Aosta (IZS PLV), 11020 Quart AO, Italy.
Riccardo OrusaIstituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d'Aosta (IZS PLV), 11020 Quart AO, Italy.
Fulvio MarsilioFaculty of Veterinary Medicine, Università degli Studi di Teramo, 64100 Teramo TE, Italy.ORCID 0000-0001-9552-1199
Vito MartellaDepartment of Veterinary Medicine, Università Aldo Moro di Bari, Valenzano, 70121 Bari BA, Italy.ORCID 0000-0002-5740-6947
Barbara Di MartinoFaculty of Veterinary Medicine, Università degli Studi di Teramo, 64100 Teramo TE, Italy.ORCID 0000-0001-6192-7166
University of Teramo · ITIstituto Zooprofilattico Sperimentale del Piemonte Liguria e Valle d'Aosta · ITUniversity of Bari Aldo Moro · IT

Funding

Italian Ministry of Health (Progetto di Ricerca Corrente 2018 IZS PLV 12/18 RC Sorveglianza epidemiologica sulla circolazione in Italia Nord-Occidentale di virus enterici a carattere zoonosico emergenti e riemergenti nell'interfaccia domestico-selvatico) IZS PLV 12/18 RC
6 · The paper itself

Abstract

In industrialized countries, increasing autochthonous infections of hepatitis E virus (HEV) are caused by zoonotic transmission of genotypes (Gts) 3 and 4, mainly through consumption of contaminated raw or undercooked pork meat. Although swine and wild boar are recognized as the main reservoir for Gt3 and Gt4, accumulating evidence indicates that other animal species, including domestic and wild ruminants, may harbor HEV. Herein, we screened molecularly and serologically serum and fecal samples from two domestic and four wild ruminant species collected in Valle d'Aosta and Piemonte regions (northwestern Italy. HEV antibodies were found in sheep (21.6%), goats (11.4%), red deer (2.6%), roe deer (3.1%), and in Alpine ibex (6.3%). Molecular screening was performed using different primer sets targeting highly conserved regions of hepeviruses and HEV RNA, although at low viral loads, was detected in four fecal specimens (3.0%, 4/134) collected from two HEV seropositive sheep herds. Taken together, the data obtained document the circulation of HEV in the geographical area assessed both in wild and domestic ruminants, but with the highest seroprevalence in sheep and goats. Consistently with results from other studies conducted in southern Italy, circulation of HEV among small domestic ruminants seems to occur more frequently than expected.

Indexed as

domestic and wild ruminantshepatitis E virus (HEV)HEV antibodiesviral RNA

Identifiers

PMID33317114
PMCPMC7764585
OpenAlexW3112896867

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.