Evidence map›Paper›PMID 33317101›Full record

ReviewMedicina (Kaunas, Lithuania)2020

Update on COVID-19 Myocarditis.

Arianne Clare C Agdamag, Jonathan B Edmiston, Victoria Charpentier, Mohammed Chowdhury, Meg Fraser, Valmiki R Maharaj, Gary S Francis, Tamas Alexy

Open access · goldAbstract readReview
In one paragraph

Review in Medicina (Kaunas, Lithuania), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 58 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. A Case of COVID-19-Induced Delayed-Onset Myocarditis.The American journal of case reports · 2022
    Article
  14. Article
  15. Review
  16. Review
  17. Prevalence and Clinical Implications of COVID-19 Myocarditis.Cardiac electrophysiology clinics · 2022
    Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Arianne Clare C AgdamagDivision of Cardiology, Department of Medicine, University of Minnesota, Minneapolis, MN 55455, USA.ORCID 0000-0002-2948-039X
Jonathan B EdmistonDepartment of Medicine, University of Minnesota, Minneapolis, MN 55455, USA.
Victoria CharpentierDepartment of Medicine, University of Minnesota, Minneapolis, MN 55455, USA.
Mohammed ChowdhuryCardiology, North Central Heart, Sioux Falls, SD 57108, USA.
Meg FraserDivision of Cardiology, Department of Medicine, University of Minnesota, Minneapolis, MN 55455, USA.
Valmiki R MaharajDivision of Cardiology, Department of Medicine, University of Minnesota, Minneapolis, MN 55455, USA.
Gary S FrancisDivision of Cardiology, Department of Medicine, University of Minnesota, Minneapolis, MN 55455, USA.
Tamas AlexyDivision of Cardiology, Department of Medicine, University of Minnesota, Minneapolis, MN 55455, USA.ORCID 0000-0001-8381-6299
University of Minnesota · USNorth Central College · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) gained worldwide attention at the end of 2019 when it was identified to cause severe respiratory distress syndrome. While it primarily affects the respiratory system, we now have evidence that it affects multiple organ systems in the human body. Cardiac manifestations may include myocarditis, life threatening arrhythmias, acute coronary syndrome, systolic heart failure, and cardiogenic shock. Myocarditis is increasingly recognized as a complication of Coronavirus-19 (COVID-19) and may result from direct viral injury or from exaggerated host immune response. The diagnosis is established similar to other etiologies, and is based on detailed history, clinical exam, laboratory findings and non-invasive imaging studies. When available, cardiac MRI is the preferred imaging modality. Endomyocardial biopsy may be performed if the diagnosis remains uncertain. Current management is mainly supportive with the potential addition of interventions recommended for severe COVID-19 disease, such as remdesivir, steroids, and convalescent plasma. In the setting of cardiogenic shock and refractory, life-threatening arrhythmias that persist despite medical therapy, advanced mechanical circulatory support devices should be considered. Ultimately, early recognition and aggressive intervention are key factors in reducing morbidity and mortality. Our management strategy is expected to evolve further as we learn more about COVID-19 disease and the associated cardiac complications.

Indexed as

COVID-19 Drug TreatmentSARS-CoV-2Adenosine MonophosphateAlanineAntiviral AgentsCOVID-19COVID-19 SerotherapyHumansImmunization, PassiveMyocarditisSteroidsAdenosine MonophosphateAlanineAntiviral AgentsremdesivirSteroidscardiogenic shockcoronavirusCOVID-19heart failuremyocarditis

Identifiers

PMID33317101
PMCPMC7764165
OpenAlexW3111880201

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.