ArticleInternational journal of molecular sciences2020
Hepatocyte-Derived Igκ Exerts a Protective Effect against ConA-Induced Acute Liver Injury.
Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 11 citations in OpenAlex.
- Immunoglobulin κ drives liver regeneration by stabilizing MYLK to maintain cytoskeletal integrity and promote hepatocyte proliferation.Journal of translational internal medicine · 2026Article
- B Cell-Derived and Non-B Cell-Derived Free Light Chains: From Generation to Biological and Pathophysiological Roles.International journal of molecular sciences · 2025Review
- IgA expressed by glomerular mesangial cells is involved in the pathogenesis of IgA nephropathy.Frontiers in immunology · 2025Article
- Hepatocyte-derived Igκ promotes HCC progression by stabilizing electron transfer flavoprotein subunit α to facilitate fatty acid β-oxidation.Journal of experimental & clinical cancer research : CR · 2024Article
- The Structure Characteristics and Function of Non B Cell-Derived Immunoglobulin.Advances in experimental medicine and biology · 2024Review
- Comparison of Non B-Ig and B-Ig.Advances in experimental medicine and biology · 2024Review
- Functions and Clinical Relevance of Liver-Derived Immunoglobulins.Advances in experimental medicine and biology · 2024Review
- Remove, Refine, Reduce: Cell Death in Biological Systems.International journal of molecular sciences · 2023Article
- Purinergic receptor P2Y12 boosts autoimmune hepatitis through hexokinase 2-dependent glycolysis in T cells.International journal of biological sciences · 2023Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
Immunoglobulin (Igκ) has been reported to be expressed in sorted liver epithelial cells of μMT mice, and the sequence characteristics of hepatocyte-derived Igκ were different from those of classical B-cell-derived Igκ. However, the physiological function of hepatocyte-derived Igκ is still unclear. The expression of Igκ was firstly identified in primary hepatocytes and normal liver cell line (NCTC1469), and hepatocyte-derived Igκ expression was elevated and displayed unique localization in hepatocytes of concanavalin A (ConA)-induced hepatitis model. Moreover,
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Registered trials
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