Evidence map›Paper›PMID 33317069›Full record

ArticleJournal of clinical medicine2020

Mortality Prediction of the CHA

Doralisa Morrone, Sonja Kroep, Fabrizio Ricci, Giulia Renda, Giuseppe Patti, Paulus Kirchhof, Ling-Hsiang Chuang, Ben van Hout, Raffaele De Caterina

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Outcomes after TAVI in patients with atrial fibrillation and a history of recent PCI: Results from the ENVISAGE-TAVI AF trial.Clinical research in cardiology : official journal of the German Cardiac Society · 2025
    Trial
  3. Trial
  4. Periprocedural Edoxaban Management and Clinical Outcomes in Patients Undergoing Transcatheter Cardiovascular Procedures in the EMIT-AF/VTE Program.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Trial
  5. CHAFrontiers in cardiovascular medicine · 2026
    Article
  6. Article
  7. Evaluation of CHAJournal of clinical medicine · 2025
    Article
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  15. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Doralisa MorroneDivision of Cardiology, Department of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa, 50124 Pisa, Italy.
Sonja KroepPharmerit-An OPEN Health Company, 3068 AV Rotterdam, The Netherlands.
Fabrizio RicciInstitute of Cardiology and Center of Excellence on Aging, G. d'Annunzio University, 66100 Chieti-Pescara, Italy.
Giulia RendaInstitute of Cardiology and Center of Excellence on Aging, G. d'Annunzio University, 66100 Chieti-Pescara, Italy.
Giuseppe PattiDepartment of Thoracic and Cardiovascular Diseases, University of Eastern Piedmont, 28100 Novara, Italy.
Paulus KirchhofUniversity of Birmingham Institute of Cardiovascular Sciences, University of Birmingham, UHB and SWBH NHS Trusts, Birmingham B15 2TT, UK.ORCID 0000-0002-1881-0197
Ling-Hsiang ChuangPharmerit-An OPEN Health Company, 3068 AV Rotterdam, The Netherlands.
Ben van HoutPharmerit-An OPEN Health Company, 3068 AV Rotterdam, The Netherlands.
Raffaele De CaterinaDivision of Cardiology, Department of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa, 50124 Pisa, Italy.ORCID 0000-0003-1637-574X

Funding

Daiichi-Sankyo Europe N.A.
6 · The paper itself

Abstract

BACKGROUND AND

objectivesAtrial fibrillation (AF) is associated with increased mortality, predictors of which are poorly characterized. We investigated the predictive power of the commonly used CHA

methodsThe PREvention oF thromboembolic events-European Registry in Atrial Fibrillation (PREFER in AF) was a prospective registry including AF patients across seven European countries. We used logistic regression to analyze the relationship between the CHA

resultsIn 5209 AF patients with complete information on both scores, average one-year mortality was 3.1%. We found strong gradients between stroke/systemic embolic events (SSE), major bleeding and-specifically-mortality for both CHA

conclusionsBoth the CHA

Indexed as

atrial fibrillationCHA2DS2-VASc scoreHAS-BLED scoremorbiditymortalityrisk scores

Identifiers

PMID33317069
PMCPMC7764787

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.