Evidence map›Paper›PMID 33316948›Full record

ReviewMolecules (Basel, Switzerland)2020

β-Carotene: Preventive Role for Type 2 Diabetes Mellitus and Obesity: A Review.

Gabriela Marcelino, David Johane Machate, Karine de Cássia Freitas, Priscila Aiko Hiane, Iriani Rodrigues Maldonade, Arnildo Pott, Marcel Arakaki Asato, Camila Jordão Candido, Rita de Cássia Avellaneda Guimarães

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
4.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 130 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Gabriela MarcelinoPost Graduate Program in Health and Development in the Central-West Region of Brazil, Federal University of Mato Grosso do Sul, Campo Grande 79070-900, Brazil.ORCID 0000-0003-0015-6083
David Johane MachateGroup of Spectroscopy and Bioinformatics Applied Biodiversity and Health (GEBABS), Graduate Program in Science of Materials, Federal University of Mato Grosso do Sul, Campo Grande 79070-900, Brazil.
Karine de Cássia FreitasPost Graduate Program in Health and Development in the Central-West Region of Brazil, Federal University of Mato Grosso do Sul, Campo Grande 79070-900, Brazil.ORCID 0000-0002-5813-6088
Priscila Aiko HianePost Graduate Program in Health and Development in the Central-West Region of Brazil, Federal University of Mato Grosso do Sul, Campo Grande 79070-900, Brazil.ORCID 0000-0003-1115-4083
Iriani Rodrigues MaldonadeLaboratory of Food Science and Technology, Brazilian Agricultural Research Corporation (Embrapa Vegetables), Brasília 70275-970, Brazil.
Arnildo PottLaboratory of Botany, Institute of Biosciences, Federal University of Mato Grosso do Sul, Campo Grande 79070-900, Brazil.
Marcel Arakaki AsatoFaculty of Medicine, Federal University of Mato Grosso do Sul, Campo Grande 79070-900, Brazil.
Camila Jordão CandidoPost Graduate Program in Health and Development in the Central-West Region of Brazil, Federal University of Mato Grosso do Sul, Campo Grande 79070-900, Brazil.ORCID 0000-0001-9837-4040
Rita de Cássia Avellaneda GuimarãesPost Graduate Program in Health and Development in the Central-West Region of Brazil, Federal University of Mato Grosso do Sul, Campo Grande 79070-900, Brazil.
Universidade Federal de Mato Grosso do Sul · BRBrazilian Agricultural Research Corporation · BR

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 001
6 · The paper itself

Abstract

Carotenoids are vital antioxidants for plants and animals. They protect cells from oxidative events and act against the inflammatory process and carcinogenesis. Among the most abundant carotenoids in human and foods is β-carotene. This carotenoid has the highest level of provitamin A activity, as it splits into two molecules of retinol through the actions of the cytosolic enzymes: β-carotene-15,15'-monooxygenase (β-carotene-15,15'-oxygenase 1) and β-carotene-9',10'-dioxygenase (β-carotene-9',10'-oxygenase 2). The literature supports the idea that β-carotene acts against type 2 diabetes mellitus, cardiovascular diseases, obesity, and metabolic syndrome. Due to the many processes involved in β-carotene biosynthesis and metabolic function, little is known about such components, since many mechanisms have not yet been fully elucidated. Therefore, our study concisely described the relationships between the consumption of carotenoids, with emphasis on β-carotene, and obesity and type 2 diabetes mellitus and its associated parameters in order to understand the preventive role of carotenoids better and encourage their consumption.

Indexed as

AnimalsAntioxidantsbeta CaroteneDiabetes Mellitus, Type 2HumansInsulin ResistanceLipid MetabolismObesityOxidative StressAntioxidantsbeta Caroteneantioxidantsdyslipidemiainsulin resistanceoxidative stress

Identifiers

PMID33316948
PMCPMC7763535
OpenAlexW3110951353

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.