Evidence map›Paper›PMID 33316929›Full record

ArticleVaccines2020

BCG Provides Short-Term Protection from Experimental Cerebral Malaria in Mice.

Julia Witschkowski, Jochen Behrends, Roland Frank, Lars Eggers, Linda von Borstel, David Hertz, Ann-Kristin Mueller, Bianca E Schneider

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Vaccines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. HarnessingVaccines · 2022
    Review
  8. Frontiers in microbiology · 2022
    Review
  9. Malaria Related Neurocognitive Deficits and Behavioral Alterations.Frontiers in cellular and infection microbiology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Julia WitschkowskiJunior Research Group Coinfection, Priority Area Infections, Research Center Borstel-Leibniz Lung Center, 23845 Borstel, Germany.
Jochen BehrendsCore Facility Fluorescence Cytometry, Research Center Borstel-Leibniz Lung Center, 23845 Borstel, Germany.ORCID 0000-0002-0648-8911
Roland FrankCentre for Infectious Diseases, Parasitology Unit, Heidelberg University Hospital, 69120 Heidelberg, Germany.
Lars EggersJunior Research Group Coinfection, Priority Area Infections, Research Center Borstel-Leibniz Lung Center, 23845 Borstel, Germany.
Linda von BorstelJunior Research Group Coinfection, Priority Area Infections, Research Center Borstel-Leibniz Lung Center, 23845 Borstel, Germany.
David HertzJunior Research Group Coinfection, Priority Area Infections, Research Center Borstel-Leibniz Lung Center, 23845 Borstel, Germany.
Ann-Kristin MuellerCentre for Infectious Diseases, Parasitology Unit, Heidelberg University Hospital, 69120 Heidelberg, Germany.
Bianca E SchneiderJunior Research Group Coinfection, Priority Area Infections, Research Center Borstel-Leibniz Lung Center, 23845 Borstel, Germany.
Research Center Borstel - Leibniz Lung Center · DEHeidelberg University · DE

Funding

Deutsche Forschungsgemeinschaft SCHN 1150/4-1
6 · The paper itself

Abstract

Clinical and experimental evidence suggests that the tuberculosis vaccine BCG offers protection against unrelated pathogens including the malaria parasite. Cerebral malaria (CM) is the most severe complication associated with

Indexed as

BCGexperimental cerebral malariaheterologous immunitynon-specific protectionPlasmodium berghei ANKA

Identifiers

PMID33316929
PMCPMC7768457
OpenAlexW3113184069

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.