Evidence map›Paper›PMID 33316917›Full record

ArticleAnimals : an open access journal from MDPI2020

Leptin System in Obese Dog Skin: A Pilot Study.

Margherita Maranesi, Antonio Di Loria, Cecilia Dall'Aglio, Diego Piantedosi, Elvio Lepri, Paolo Ciaramella, Francesca Mercati

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Margherita MaranesiDepartment of Veterinary Medicine, University of Perugia, via San Costanzo 4, 06126 Perugia, Italy.ORCID 0000-0002-1727-4118
Antonio Di LoriaDepartment of Veterinary Medicine and Animal Productions, University Federico II of Napoli, via F. Delpino 1, 080137 Napoli, Italy.ORCID 0000-0001-6947-0287
Cecilia Dall'AglioDepartment of Veterinary Medicine, University of Perugia, via San Costanzo 4, 06126 Perugia, Italy.ORCID 0000-0001-6451-3751
Diego PiantedosiDepartment of Veterinary Medicine and Animal Productions, University Federico II of Napoli, via F. Delpino 1, 080137 Napoli, Italy.
Elvio LepriDepartment of Veterinary Medicine, University of Perugia, via San Costanzo 4, 06126 Perugia, Italy.ORCID 0000-0001-8478-8154
Paolo CiaramellaDepartment of Veterinary Medicine and Animal Productions, University Federico II of Napoli, via F. Delpino 1, 080137 Napoli, Italy.ORCID 0000-0002-5518-5378
Francesca MercatiDepartment of Veterinary Medicine, University of Perugia, via San Costanzo 4, 06126 Perugia, Italy.ORCID 0000-0002-8799-1200
University of Perugia · ITUniversity of Naples Federico II · IT

Funding

Università degli Studi di Perugia Ricerca di base 2018, Project "Le adipochine come markers diagnostici nell'obesità: studi clinici e molecolari", scientific coordinator Prof. Francesca Mercati
6 · The paper itself

Abstract

Obesity predisposes to several health problems including skin diseases. However, information on the relationship between obesity and skin disorders in pets is very scarce. Leptin (LEP) is mainly produced by adipose tissue and has a prominent role in skin biology. This study evaluated the LEP system in the skin of obese dogs compared to normal-weight animals. The investigation was carried out on 10 obese (Obese group) and 10 normal-weight (Normal-weight group) dogs through Real-time PCR and immunohistochemistry. Cells of skin associated immune system were also evaluated. No differences were evidenced between the two groups as well as skin inflammation.

Indexed as

dogimmunohistochemistryintegumentary systemLEPLEPRRT-PCR

Identifiers

PMID33316917
PMCPMC7764193
OpenAlexW3111945487

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.