Observational studyNutrients2020
Low 25-Hydroxyvitamin D Levels on Admission to the Intensive Care Unit May Predispose COVID-19 Pneumonia Patients to a Higher 28-Day Mortality Risk: A Pilot Study on a Greek ICU Cohort.
Observational study in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 5 syntheses or guidelines pooled it, 49 citations in OpenAlex.
- The effect of vitamin D supplementation on mortality and intensive care unit admission of COVID-19 patients. A systematic review, meta-analysis and meta-regression.Diabetes/metabolism research and reviews · 2022Pooled it
- Vitamin D and SARS-CoV2 infection, severity and mortality: A systematic review and meta-analysis.PloS one · 2022Pooled it
- Coronavirus Disease 2019 as Cause of Viral Sepsis: A Systematic Review and Meta-Analysis.Critical care medicine · 2021Pooled it
- The link between COVID-19 and VItamin D (VIVID): A systematic review and meta-analysis.Metabolism: clinical and experimental · 2021Pooled it
- Vitamin D Status and SARS-CoV-2 Infection and COVID-19 Clinical Outcomes.Frontiers in public health · 2021Pooled it
- High-dose versus standard-dose vitamin D supplementation in older adults with COVID-19 (COVIT-TRIAL): A multicenter, open-label, randomized controlled superiority trial.PLoS medicine · 2022Trial
- Vitamin D: A key player in COVID-19 immunity and lessons from the pandemic to combat immune-evasive variants.Inflammopharmacology · 2024Review
- Efficiency of the Vitamin D Status Diagnosticator amongst Geriatric Patients with COVID-19.Nutrients · 2024Article
- High-dose vitamin D supplementation in patients with COVID-19: A meta-analysis of randomized controlled trials.Food science & nutrition · 2024Article
- Vitamin D Status and Mortality from SARS CoV-2: A Prospective Study of Unvaccinated Caucasian Adults.Nutrients · 2022Article
- Vitamin D, infections and immunity.Reviews in endocrine & metabolic disorders · 2022Review
- The Role of Vitamin D in Supporting Health in the COVID-19 Era.International journal of molecular sciences · 2022Review
- The Role of Nutrients in Prevention, Treatment and Post-Coronavirus Disease-2019 (COVID-19).Nutrients · 2022Review
- Nutritional risk of vitamin D, vitamin C, zinc, and selenium deficiency on risk and clinical outcomes of COVID-19: A narrative review.Clinical nutrition ESPEN · 2022Review
- The Covid-19 infection: An opportunity to develop systematic vitamin D supplementation in psychiatry.L'Encephale · 2022Article
- 25-Hydroxyvitamin D level is associated with mortality in patients with critical COVID-19: a prospective observational study in Mexico City.Nutrition research and practice · 2021Article
- Corrigendum to: Influence of 25‑hydroxy-cholecalciferol levels on SARS-CoV-2 infection and COVID-19 severity: A systematic review and meta-analysis [EClinicalMedicine 37 (2021) 100,967].EClinicalMedicine · 2021Article
- Vitamin D in infectious complications in critically ill patients with or without COVID-19.Metabolism open · 2021Article
- Influence of 25-hydroxy-cholecalciferol levels on SARS-CoV-2 infection and COVID-19 severity: A systematic review and meta-analysis.EClinicalMedicine · 2021Article
- Bad Prognosis in Critical Ill Patients with COVID-19 during Short-Term ICU Stay regarding Vitamin D Levels.Nutrients · 2021Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We aimed to examine whether low intensive care unit (ICU) admission 25-hydroxyvitamin D (25(OH)D) levels are associated with worse outcomes of COVID-19 pneumonia. This was a prospective observational study of SARS-CoV2 positive critically ill patients treated in a multidisciplinary ICU. Thirty (30) Greek patients were included, in whom 25(OH)D was measured on ICU admission. Eighty (80%) percent of patients had vitamin D deficiency, and the remaining insufficiency. Based on 25(OH)D levels, patients were stratified in two groups: higher and lower than the median value of the cohort (15.2 ng/mL). The two groups did not differ in their demographic or clinical characteristics. All patients who died within 28 days belonged to the low vitamin D group. Survival analysis showed that the low vitamin D group had a higher 28-day survival absence probability (log-rank test,
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