ArticleJournal of Korean medical science2020
Hypertension-Mediated Organ Damage and Long-term Cardiovascular Outcomes in Asian Hypertensive Patients without Prior Cardiovascular Disease.
Article in Journal of Korean medical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06098300 (Effects of Change in Blood Pressure on Retinal Capillary Rarefaction in Patients With Arterial Hypertension - a Pilot Study), which is not on this map. Cited by 14 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Change in Blood Pressure on Retinal Capillary Rarefaction in Patients With Arterial Hypertension - a Pilot Study
Who cites it
14 citing papers in PubMed, 14 citations in OpenAlex.
- Article
- Diagnostic Testing Patterns Influence the Detected Burden of Hypertension-Mediated Organ Damage in Hospitalized Hypertensive Patients.Journal of clinical hypertension (Greenwich, Conn.) · 2026Article
- Stroke risk in patients with hypertensive retinopathy: a systematic review and meta-analysis.BMJ neurology open · 2026Article
- Effects of a transformative learning theory-based health literacy enhancement program on self-management behaviors and blood pressure in adults with uncontrolled hypertension in Thailand: A cluster randomized controlled trial.Belitung nursing journal · 2026Article
- Association between hypertensive retinopathy and left ventricular hypertrophy.Bioinformation · 2026Article
- Interaction between 24 h Urinary Free Cortisol and Obesity in Hypertension-Mediated Organ Damage in Patients with Untreated Hypertension.Reviews in cardiovascular medicine · 2025Article
- HyMNet: A Multimodal Deep Learning System for Hypertension Prediction Using Fundus Images and Cardiometabolic Risk Factors.Bioengineering (Basel, Switzerland) · 2024Article
- Cumulative blood pressure load and hypertensive nephropathy in Han Chinese hypertensive patients.Journal of clinical hypertension (Greenwich, Conn.) · 2024Article
- Gender Difference of Blood Pressure Control Rate and Clinical Prognosis in Patients With Resistant Hypertension: Real-World Observation Study.Journal of Korean medical science · 2023Article
- Prevalence and Characterisation of Severe Left Ventricular Hypertrophy Diagnosed by Echocardiography in Hypertensive Patients.Journal of clinical medicine · 2022Article
- RSSDI Guidelines for the management of hypertension in patients with diabetes mellitus.International journal of diabetes in developing countries · 2022Review
- Impact of underweight on 3-year all-cause mortality in patients with acute severe hypertension: a retrospective cohort study.Scientific reports · 2022Article
- Hypertension-Mediated Organ Damage: Prevalence, Correlates, and Prognosis in the Community.Hypertension (Dallas, Tex. : 1979) · 2022Article
- Clinical Characteristics and Predictors of All-Cause Mortality in Patients with Hypertensive Urgency at an Emergency Department.Journal of clinical medicine · 2021Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
backgroundHypertension-mediated organ damage (HMOD), comprising structural and functional changes in arteries or end organs, is a marker of cardiovascular (CV) disease. However, there are limited data on evaluation of risk of CV disease regarding HMOD, especially in Asians. We sought to investigate the association between CV events and HMOD, and we tried to determine the most important diagnostic marker among the component of HMOD for prevention of mortality and CV events in treated Korean hypertensive patients.
methodsFrom January 2008 to December 2010, a total of 35,000 hypertensive Vietnamese War veterans who consecutively visited our hospital for medical check-up were reviewed, and 6,158 patients without established CV disease were enrolled. The patients were divided into two groups as follows: HMOD group (n = 766) and non-HMOD group (n = 5,392). The primary outcome was all-cause death.
resultsMedian age was 63.3 years (interquartile range [IQR], 61.4-65.4), and median follow-up was 6.6 years (IQR, 5.9-7.2). Patients with old age, diabetes, and chronic kidney disease were more prevalent in the HMOD group than in the non-HMOD group (all
conclusionHMOD was associated with increased risk of mortality and CV events. Proteinuria was the most powerful independent risk factor for all-cause death, and the degree of proteinuria and mortality rate were proportional. Our data suggest that monitoring of the proteinuria is important to predict long-term CV events in hypertensive patients.
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