Evidence map›Paper›PMID 33316808›Full record

ArticleComplementary medicine research2021

Low Vitamin D Status in a Cancer Patient Population from Franconia, Germany.

Rainer Johannes Klement, Petra S Koebrunner, Kelley Krage, Reinhart A Sweeney

Open access · bronzeAbstract read
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Article in Complementary medicine research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Rainer Johannes KlementDepartment of Radiation Oncology, Leopoldina Hospital, Schweinfurt, Germany, rainer_klement@gmx.de.
Petra S KoebrunnerDepartment of Radiation Oncology, Leopoldina Hospital, Schweinfurt, Germany.
Kelley KrageDepartment of Radiation Oncology, Leopoldina Hospital, Schweinfurt, Germany.
Reinhart A SweeneyDepartment of Radiation Oncology, Leopoldina Hospital, Schweinfurt, Germany.
Leopoldina Krankenhaus Schweinfurt · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVitamin D has been shown to be associated with reduced risk and severity of COVID-19 and exerts regulating effects on all hallmarks of cancer. The goal of this study was to analyze the vitamin D status of a cancer patient cohort from our clinic in the Franconian region, Germany.

methods25-hydroxyvitamin D concentrations were available for 116 patients included in prospective trials in our clinic. Associations of vitamin D with anthropometric and blood parameters were investigated using Kendall's τ correlation coefficients and linear regression.

resultsA total of 57 patients (49.1%) were vitamin D deficient (<20 ng/mL), and 92.2% did not meet the recommended vitamin D level of 40 ng/mL. There was a strong negative association between vitamin D and leukocyte count (τ = -0.173, p = 0.007) and C-reactive protein concentration (τ = -0.172, p = 0.007). In linear regression, the most important variables for predicting vitamin D levels were (in order of decreasing importance) season, fat mass index, platelet, and leukocyte count.

conclusionsDespite appeals towards medical societies to target widespread vitamin D deficiency in Germany more than 10 years ago, our data indicate that these have been without avail. Low vitamin D levels in cancer patients should be corrected using reasonable sun exposure and supplements.

Indexed as

AdultAgedCOVID-19C-Reactive ProteinDietary SupplementsFemaleHumansMaleMiddle AgedNeoplasmsProspective StudiesSARS-CoV-2Vitamin DVitamin D Deficiency25-hydroxyvitamin DC-Reactive ProteinVitamin DCalcitriolCholecalciferolCOVID-19RadiotherapySARS-CoV-2

Identifiers

PMID33316808
PMCPMC7801956
OpenAlexW3112455181

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.