Evidence map›Paper›PMID 33316537›Full record

ArticleNeoplasia (New York, N.Y.)2021

SUMOylation is essential for Sirt2 tumor-suppressor function in neuroblastoma.

Wenmei Lu, Qian Wang, Ci Xu, Haihua Yuan, Qiang Fan, Biying Chen, Renjie Cai, Danhong Wu, Ming Xu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neoplasia (New York, N.Y.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 24 citations in OpenAlex.

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  9. Fbxo45-mediated NP-STEPMolecular oncology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Wenmei LuDepartment of Oncology, Shanghai 9th People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Department of Neurology, Shanghai Fifth People's Hospital, Fudan University, Shanghai, China.
Qian WangDepartment of Oncology, Shanghai 9th People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Ci XuDepartment of Oncology, Shanghai 9th People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Haihua YuanDepartment of Oncology, Shanghai 9th People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Qiang FanDepartment of General Surgery, Shanghai 9th People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Biying ChenDepartment of Oncology, Shanghai 9th People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Renjie CaiDepartment of Oncology, Shanghai 9th People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Danhong WuDepartment of Neurology, Shanghai Fifth People's Hospital, Fudan University, Shanghai, China. Electronic address: danhongwu@fudan.edu.cn.
Ming XuDepartment of Oncology, Shanghai 9th People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address: mingxu@shsmu.edu.cn.
Shanghai Jiao Tong University · CNFudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

SUMOylation is an important post-translational modification that participates in a variety of cellular physiological and pathological processes in eukaryotic cells. Sirt2, a NAD

Indexed as

AnimalsCell LineCell MovementCell ProliferationDisease Models, AnimalGene ExpressionHumansMiceNeuroblastomap38 Mitogen-Activated Protein KinasesPrognosisProtein Processing, Post-TranslationalProto-Oncogene Proteins c-aktSignal TransductionSirtuin 2Sumoylationp38 Mitogen-Activated Protein KinasesProto-Oncogene Proteins c-aktSirtuin 2TOR Serine-Threonine KinasesTumor Suppressor ProteinsAcetylationCell SignalingNeuroblastomaSirt2SUMOylation

Identifiers

PMID33316537
PMCPMC7736920
OpenAlexW3112321440

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.