ArticleEuropean journal of neurology2021
Early shunt surgery improves survival in idiopathic normal pressure hydrocephalus.
Article in European journal of neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed, 66 citations in OpenAlex.
- A Randomized Trial of Shunting for Idiopathic Normal-Pressure Hydrocephalus.The New England journal of medicine · 2025Trial
- Ethical aspects of waiting lists in neurosurgery.Acta neurochirurgica · 2026Review
- Clinical characteristics and outcomes after shunt surgery in idiopathic normal pressure hydrocephalus with or without prior cerebrospinal fluid tap testing: a single-center follow-up study of 481 patients.Fluids and barriers of the CNS · 2026Article
- Clinical and Radiological Evolution of Idiopathic Normal Pressure Hydrocephalus: A Critical Review.Movement disorders clinical practice · 2026Review
- Role of the Functional Gait Assessment in Validating Item Difficulty Hierarchy and Fall Risk for Idiopathic Normal Pressure Hydrocephalus.Movement disorders clinical practice · 2025Article
- Time Course of Symptoms in Normal-Pressure Hydrocephalus: A Systematic Review.Diagnostics (Basel, Switzerland) · 2025Review
- Long-term gait improvement following a CSF tap test in idiopathic normal pressure hydrocephalus patients: an analysis of clinical outcomes.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Article
- Effect of ventricular volume on cerebrospinal fluid Alzheimer's disease biomarkers in patients with idiopathic normal pressure hydrocephalus.Journal of Alzheimer's disease : JAD · 2025Article
- Long-term outcomes of ventriculoperitoneal shunt therapy in idiopathic normal pressure hydrocephalus.BMC surgery · 2025Article
- Fundoscopy as a diagnostic biomarker in idiopathic normal pressure hydrocephalus: a pilot study.BMJ neurology open · 2025Article
- Physical activity and gait in patients with idiopathic normal pressure hydrocephalus: a literature review.Frontiers in neurology · 2025Review
- Survival After Shunt Therapy in Normal-Pressure Hydrocephalus: A Meta-Analysis of 1614 Patients.Neurology international · 2024Review
- Modeling CSF circulation and the glymphatic system during infusion using subject specific intracranial pressures and brain geometries.Fluids and barriers of the CNS · 2024Article
- Deep learning assessment of disproportionately enlarged subarachnoid-space hydrocephalus in Hakim's disease or idiopathic normal pressure hydrocephalus.Radiology advances · 2024Article
- Comparing the Long-Term Cardiovascular Outcomes of Lumbo-Peritoneal, Ventriculo-Peritoneal, or Non-Shunting Treatment after Idiopathic Normal Pressure Hydrocephalus: A Nationwide Retrospective Cohort Study.International journal of medical sciences · 2024Article
- Automatic assessment of disproportionately enlarged subarachnoid-space hydrocephalus from 3D MRI using two deep learning models.Frontiers in aging neuroscience · 2024Article
- Association of gait and cognition after surgery in patients with idiopathic normal pressure hydrocephalus.Scientific reports · 2023Article
- Levels of inflammatory cytokines MCP-1, CCL4, and PD-L1 in CSF differentiate idiopathic normal pressure hydrocephalus from neurodegenerative diseases.Fluids and barriers of the CNS · 2023Article
- Diffusion tensor imaging helps identify shunt-responsive normal pressure hydrocephalus patients among probable iNPH cohort.Neurosurgical review · 2023Article
- Novel cerebrospinal fluid biomarkers correlating with shunt responsiveness in patients with idiopathic normal pressure hydrocephalus.Fluids and barriers of the CNS · 2023Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeTo examine the effect of delayed compared to early planning of shunt surgery on survival, in patients with idiopathic normal pressure hydrocephalus (iNPH), a long-term follow-up case-control study of patients exposed to a severe delay of treatment was performed.
methodsIn 2010-2011 our university hospital was affected by an administrative and economic failure that led to postponement of several elective neurosurgical procedures. This resulted in an unintentional delay of planning of treatment for a group of iNPH patients, referred to as iNPH
resultsMedian follow-up time was 6.0 years. Crude 4-year mortality was 39.4% in iNPH
conclusionsThe present data indicate that shunt surgery is effective in iNPH and that early treatment increases survival.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.