Evidence map›Paper›PMID 33315896›Full record

ArticlePLoS neglected tropical diseases2020

Cost of a new method of active screening for human African trypanosomiasis in the Democratic Republic of the Congo.

Rian Snijders, Alain Fukinsia, Yves Claeys, Alain Mpanya, Epco Hasker, Filip Meheus, Erick Miaka, Marleen Boelaert

Open access · goldAbstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Rian SnijdersDepartment of Public Health, Institute of Tropical Medicine, Antwerp, Belgium.ORCID 0000-0002-2432-9818
Alain FukinsiaProgramme National de Lutte Contre la Trypanosomiase Humaine Africaine, Kinshasa, the Democratic Republic of Congo.
Yves ClaeysDepartment of Public Health, Institute of Tropical Medicine, Antwerp, Belgium.
Alain MpanyaProgramme National de Lutte Contre la Trypanosomiase Humaine Africaine, Kinshasa, the Democratic Republic of Congo.
Epco HaskerDepartment of Public Health, Institute of Tropical Medicine, Antwerp, Belgium.
Filip MeheusSection of Cancer Surveillance, International Agency for Research on Cancer, Lyon, France.
Erick MiakaProgramme National de Lutte Contre la Trypanosomiase Humaine Africaine, Kinshasa, the Democratic Republic of Congo.ORCID 0000-0001-7624-7905
Marleen BoelaertDepartment of Public Health, Institute of Tropical Medicine, Antwerp, Belgium.
Instituut voor Tropische Geneeskunde · BEProgramme National Multisectoriel de Lutte contre le sida · CDCentre international de recherche sur le cancer · FR

Funding

World Health Organization 001
6 · The paper itself

Abstract

backgroundHuman African trypanosomiases caused by the Trypanosoma brucei gambiense parasite is a lethal disease targeted for eradication. One of the main disease control strategies is active case-finding through outreach campaigns. In 2014, a new method for active screening was developed with mini, motorcycle-based, teams. This study compares the cost of two active case-finding approaches, namely the traditional mobile teams and mini mobile teams, in the two health districts of the Democratic Republic of the Congo.

methodsThe financial and economic costs of both approaches were estimated from a health care provider perspective. Cost and operational data were collected for 12 months for 1 traditional team and 3 mini teams. The cost per person screened and diagnosed was calculated and univariate sensitivity analysis was conducted to identify the main cost drivers.

resultsDuring the study period in total 264,630 people were screened, and 23 HAT cases detected. The cost per person screened was lower for a mini team than for a traditional team in the study setting (US$1.86 versus US$2.08). A comparable result was found in a scenario analysis, assuming both teams would operate in a similar setting, with the cost per person screened by a mini team 15% lower than the cost per person screened by a traditional team (1.86 $ vs 2.14$). The main explanations for this lower cost are that mini teams work with fewer human resources, cheaper means of transportation and do not perform the Capillary Tube Centrifugation test or card agglutination test dilutions. DISCUSSION: Active HAT screening with mini mobile teams has a lower cost and could be a cost-effective alternative for active case-finding. Further research is needed to determine if mini mobile teams have similar or better yields than traditional mobile teams in terms of detections and cases successfully treated.

Indexed as

Agglutination TestsDelivery of Health CareDemocratic Republic of the CongoHealth Care CostsHumansMass ScreeningSensitivity and SpecificityTrypanosoma brucei gambienseTrypanosomiasis, African

Identifiers

PMID33315896
PMCPMC7769601
OpenAlexW3113285448

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.