ArticlePloS one2020
The effect of psychological distress on IVF outcomes: Reality or speculations?
Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
60 citing papers in PubMed, 4 syntheses or guidelines pooled it, 99 citations in OpenAlex.
- Is stress different in infertile women and men? A systematic review and meta-analysis.BMC public health · 2025Pooled it
- Prevalence of psychological problems among individuals and couples during assisted reproductive technology(ART) treatment: a systematic review and meta-analysis.Journal of assisted reproduction and genetics · 2025Pooled it
- Effects of emotions on IVF/ICSI outcomes in infertile women: a systematic review and meta-analysis.Journal of assisted reproduction and genetics · 2025Pooled it
- Research Performance in Reproductive Biomedicine: A National Scientometrics Study.International journal of fertility & sterility · 2023Pooled it
- Effect of guided imagery relaxation on stress in infertile women candidates for in vitro fertilization.BMC psychology · 2025Trial
- Stress management through cognitive reconstruction and positive thinking in women with recurrent failed In Vitro Fertilization: a randomized controlled trial.BMC psychiatry · 2025Trial
- The prevalence of depressive symptoms in surrogate mothers following child relinquishment: a systematic review and meta-analysis.Annals of medicine and surgery (2012) · 2026Article
- Sleep Quality, Psychological Resilience, and Attachment Dimensions in Women with Unexplained and Male Factor Infertility: A Cross-Sectional Study.Journal of clinical medicine · 2026Article
- Information overload and pregnancy outcomes in IVF: psychological distress as an explanatory pathway.Scientific reports · 2026Article
- Developing and evaluating the effectiveness of a web-based application to improve the mental health of infertile women: a multi-phase study protocol.Reproductive health · 2026Article
- Moderating Role of Psychological Flexibility in the Relationship Between Intolerance of Uncertainty and Perceived Stress Among Women Undergoing in Vitro Fertilization Treatment.Brain and behavior · 2026Article
- Effects of Uncertainty on Depression in Women Undergoing Assisted Reproductive Technology: The Mediating Role of Perceived Stigma and the Moderated Mediation by Spousal Support.Nursing & health sciences · 2026Article
- Endometrial cortisol level and its relationship with psychological stress, molecular tissue changes, and clinical outcomes in infertile women.Scientific reports · 2026Article
- Mapping the symptom network of anxiety, depression, somatic symptoms and sleep disturbances in 15,642 infertile women: a retrospective cohort study identifying targets for fertility care.Frontiers in public health · 2026Article
- Maternal Psychological Distress and Repeated Implantation Failure: A Mini Review : Short title: Maternal Distress and Implantation Failure.Galen medical journal · 2026Review
- Boosting psychological well-being in infertile women undergoing IVF through Fordyce happiness counseling: a quasi-experimental approach in Zahedan, Southeast Iran.Preventive medicine reports · 2026Article
- Perceived infertility-related stress, partner attachment, and psychological distress among women undergoing in-vitro fertilization treatment: a latent profile and mediation analysis.BMC women's health · 2025Article
- Chromosomal Abnormalities in Couples Experiencing Recurrent Implantation Failure in West of Iran: A Case-Control Study.Molecular genetics & genomic medicine · 2025Article
- Using Social Media Data to Assess the Impact of Infertility on French Patients' Quality of Life: Retrospective Observational Study.Journal of medical Internet research · 2025Observational
- Silent battles, global insights: anxiety and depression in the world of assisted reproduction.Journal of assisted reproduction and genetics · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionInfertility is a problem that affects millions of people worldwide. The aim of this study was to assess the effect of stress, depression and anxiety on the IVF outcomes in Kazakhstan.
methodsThe prospective cohort study was performed using questionnaires to assess psychological distress in 304 infertile female in three different cities in Kazakhstan.
resultsThe average age of participants was 33.7 years with infertility duration of 5.9 years. Regarding stress, depression and anxiety we found that more than 80% of all respondents had CES-D score higher than 16, indicating that they are at risk of developing clinical depression. On average, FPI subscales' scores, global stress score and anxiety scale (STAI-S and STAI-T) scores were statistically significantly higher among not pregnant women than pregnant women. Similarly, in simple logistic regression analysis all FPI subscales scores, global stress scale score and anxiety scales' scores were negatively associated with clinical pregnancy.
conclusionRates of stress, anxiety and depression among IVF patients are higher than in general population. If the level of infertility-related stress is higher, IVF success rate is lower. Findings of our study indicate the need for the specific psychological interventions for all infertility women, to improve IVF success rate.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.