Evidence map›Paper›PMID 33315518›Full record

ArticleHuman vaccines & immunotherapeutics2021

The effect of hepatitis B vaccination after five years on an entire population in an insular region of Southeast China.

Ying Liu, Jingjing Ren, Zikang Wu, Lingzhi Shen, Huan Shan, Xuewei Dai, Jing Li, Yan Qiu, Wen Ren, Jun Yao and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Human vaccines & immunotherapeutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 2 countries.

Ying LiuThe First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.ORCID 0000-0003-2408-3712
Jingjing RenThe First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.ORCID 0000-0002-6427-4364
Zikang WuWomen's Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Lingzhi ShenDepartment of Immunology, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, China.
Huan ShanDepartment of Quality Management, Zhejiang Hospital, Hangzhou, China.
Xuewei DaiJingdezhen Center for Disease Control and Prevention, Jingdezhen, Jiangxi, China.
Jing LiDepartment of Information, Zhejiang Hospital, Hangzhou, China.
Yan QiuThe First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.ORCID 0000-0001-7996-4109
Wen RenThe First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.ORCID 0000-0003-0096-3782
Jun YaoDepartment of Immunology, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, China.
Lanjuan LiState Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.
Zhejiang University · CNZhejiang Center for Disease Control and Prevention · CNZhejiang Hospital · CNJingdezhen University · CNState Key Laboratory of Diagnosis and Treatment of Infectious DiseasesWomen's Hospital, School of Medicine, Zhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prevalence of hepatitis B (HB) remains high among adults in insular regions of southeast China. To address this issue, large-scale HB vaccination was implemented in Putuo County of Zhoushan City in 2013. To examine the effects of this large-scale HB vaccination, a cross-sectional serological survey was conducted on two isolated islands, Putuo (intervention group) and Dinghai (control group) Counties of Zhoushan City in southeastern China five years later. The data showed lower prevalence of HBsAg and negative results for all HBV markers in the intervention group compared to the control group (4.2% and 6.0%, 20.8% and 33.0%), while the positive rate for anti-HBs and only anti-HBs were higher (68.4% and 53.4%, 47.9% and 34.3%). Therefore, large-scale adult HB vaccination could lower the HB epidemic level. However, the proportion of susceptible people who were negative for all HBV markers remained high. Hence, several additional measures to limit the spread of HBV should be taken by the government.

Indexed as

Hepatitis BHepatitis B AntibodiesAdultChinaCross-Sectional StudiesHepatitis B Surface AntigensHepatitis B VaccinesHepatitis B virusHumansVaccinationHepatitis B AntibodiesHepatitis B Surface AntigensHepatitis B VaccinesHepatitis B virusimmune effectimmunizationvaccinationvaccine

Identifiers

PMID33315518
PMCPMC8078683
OpenAlexW3112314413

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.