Evidence map›Paper›PMID 33315195›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2021

Fetal Growth Plate Cartilage : Histological and Immunohistochemical Techniques.

Zachary Tata, Christophe Merceron, Ernestina Schipani

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 69% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Zachary TataDepartments of Orthopedic Surgery, Medicine and Cell and Developmental Biology, University of Michigan School of Medicine, Ann Arbor, MI, USA.
Christophe MerceronDepartments of Orthopedic Surgery, Medicine and Cell and Developmental Biology, University of Michigan School of Medicine, Ann Arbor, MI, USA.
Ernestina SchipaniDepartments of Orthopedic Surgery, Medicine and Cell and Developmental Biology, University of Michigan School of Medicine, Ann Arbor, MI, USA. eschipan@med.umich.edu.
University of Michigan–Ann Arbor · US

Funding

Structure, Composition, & Histology Core - Core BP30AR069620 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KARL J JEPSEN · 2016 to 2026
$8.4M
NIAMS NIH HHS P30 AR069620
6 · The paper itself

Abstract

Skeletal development is a tightly regulated process that primarily occurs through two distinct mechanisms. In intramembranous ossification, mesenchymal progenitors condense and transdifferentiate directly into osteoblasts, giving rise to the flat bones of the skull. The majority of the skeleton develops through endochondral ossification, in which mesenchymal progenitors give rise to a cartilaginous template that is gradually replaced by bone. The study of these processes necessitates a suitable animal model, a requirement to which the mouse is admirably suited. Their rapid reproductive ability, developmental and physiologic similarity to humans, and easily manipulated genetics all contribute to their widespread use. Outlined here are the most common histological and immunohistochemical techniques utilized in our laboratory for the isolation and analysis of specimens from the developing murine skeleton.

Indexed as

FetusAnimalsBiomarkersCell ProliferationChondrocytesFluorescent Antibody TechniqueGrowth PlateImmunohistochemistryMiceBiomarkersCartilageChondrocyteDevelopmentGrowth plateHistologyImmunohistochemistry

Identifiers

PMID33315195
OpenAlexW3113322747

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.