Evidence map›Paper›PMID 33315190›Full record

ArticleChild psychiatry and human development2021

Effectiveness of Behaviour Therapy for Children and Adolescents with Tourette Syndrome and Chronic Tic Disorder in a Naturalistic Setting.

Per Andrén, Vera Wachtmeister, Julia Franzé, Caroline Speiner, Lorena Fernández de la Cruz, Erik Andersson, Elles de Schipper, Daniel Rautio, Maria Silverberg-Mörse, Eva Serlachius and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Child psychiatry and human development, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Guideline
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Per AndrénDepartment of Clinical Neuroscience, Karolinska Institutet, Child and Adolescent Psychiatry Research Center, Gävlegatan 22, 113 30, Stockholm, Sweden. per.andren@ki.se.ORCID 0000-0003-1358-0166
Vera WachtmeisterStockholm Health Care Services, Region Stockholm, Stockholm, Sweden.
Julia FranzéDepartment of Clinical Neuroscience, Division of Psychology, Karolinska Institutet, Stockholm, Sweden.
Caroline SpeinerDepartment of Clinical Neuroscience, Division of Psychology, Karolinska Institutet, Stockholm, Sweden.
Lorena Fernández de la CruzDepartment of Clinical Neuroscience, Karolinska Institutet, Child and Adolescent Psychiatry Research Center, Gävlegatan 22, 113 30, Stockholm, Sweden.
Erik AnderssonDepartment of Clinical Neuroscience, Karolinska Institutet, Child and Adolescent Psychiatry Research Center, Gävlegatan 22, 113 30, Stockholm, Sweden.
Elles de SchipperDepartment of Clinical Neuroscience, Karolinska Institutet, Child and Adolescent Psychiatry Research Center, Gävlegatan 22, 113 30, Stockholm, Sweden.
Daniel RautioDepartment of Clinical Neuroscience, Karolinska Institutet, Child and Adolescent Psychiatry Research Center, Gävlegatan 22, 113 30, Stockholm, Sweden.
Maria Silverberg-MörseStockholm Health Care Services, Region Stockholm, Stockholm, Sweden.
Eva SerlachiusDepartment of Clinical Neuroscience, Karolinska Institutet, Child and Adolescent Psychiatry Research Center, Gävlegatan 22, 113 30, Stockholm, Sweden.
David Mataix-ColsDepartment of Clinical Neuroscience, Karolinska Institutet, Child and Adolescent Psychiatry Research Center, Gävlegatan 22, 113 30, Stockholm, Sweden.
Karolinska Institutet · SEStockholm Health Care Services · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is unclear if the results of randomised controlled trials (RCTs) of behaviour therapy (BT) for Tourette syndrome (TS) and chronic tic disorder (CTD) can be generalised to naturalistic clinical settings and are durable long-term. In this naturalistic study, 74 young people with TS/CTD received BT at a specialist clinic. Data were collected at baseline, post-treatment, and at 3-, 6-, and 12-month follow-ups. Measures included the Yale Global Tic Severity Scale (YGTSS) and the Clinical Global Impression-Improvement scale (CGI-I), amongst others. Tic severity and tic-related impairment improved after treatment, with large within-group effect sizes. At post-treatment, 57% of the participants were classified as treatment responders according to the CGI-I. Tic severity and tic-related impairment improved further through the follow-up, with 75% treatment responders at the 12-month follow-up. BT is an effective and durable treatment for young people with TS/CTD in a naturalistic specialist clinical setting, with comparable effects to RCTs.

Indexed as

Tic DisordersTourette SyndromeAdolescentBehavior TherapyChildHumansSeverity of Illness IndexTreatment OutcomeBehaviour therapyExposure with response preventionHabit reversal trainingTic disordersTourette syndrome

Identifiers

PMID33315190
PMCPMC8238753
OpenAlexW3112796422

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.