Evidence map›Paper›PMID 33314940›Full record

ArticleSouth African family practice : official journal of the South African Academy of Family Practice/Primary Care2020

Paediatric atopic eczema (atopic dermatitis) in South Africa: A practical algorithm for the management of mild-to-moderate disease in daily clinical practice.

Susanna M Kannenberg, Sarah Karabus, Willem I Visser, Jamilabibi Aboobaker, Magdalena M Kriel, Michael Levin, Basil Magigaba, Ahmed Manjra, Rupesh Misra, Pholile Mpofu and 2 more

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Article in South African family practice : official journal of the South African Academy of Family Practice/Primary Care, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

12 authors.

Susanna M KannenbergDivision of Dermatology, Department of Medicine, Faculty of Health Sciences, Stellenbosch University, Cape Town. surethak@sun.ac.za.
Sarah Karabus
Willem I Visser
Jamilabibi Aboobaker
Magdalena M Kriel
Michael Levin
Basil Magigaba
Ahmed Manjra
Rupesh Misra
Pholile Mpofu
Azwitamisi Tshigabe
Thomas Luger

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAtopic eczema (AE) is a chronic, highly pruritic, inflammatory skin condition with increasing prevalence worldwide. Atopic eczema mostly affects children, impairing quality of life with poor disease control leading to progression of other atopic disorders. As most patients in South Africa have no access to specialist healthcare, a practical approach is needed for the management of mild-to-moderate AE in paediatric patients for daily clinical practice.

methodsA panel of experts in AE convened to develop a practical algorithm for the management of AE for children and adolescents in South Africa.

resultsRegular moisturising with an oil-based emollient remains the mainstay of AE treatment. Severe AE flares should be managed with topical corticosteroids (TCSs). For mild-to-moderate AE flares in sensitive skin areas, a topical calcineurin inhibitor (TCI) should be applied twice daily from the first signs of AE until complete resolution. Topical corticosteroids may be used when TCIs are unavailable. In non-sensitive skin areas, TCSs should be used for mild-to-moderate AE, but TCIs twice daily may be considered. Proactive maintenance treatment with low-dose TCI or TCS 2-3 times weekly and the liberal use of emollients is recommended for patients with recurrent flares.

conclusionsThis algorithm aims to simplify treatment of paediatric AE, optimising clinical outcomes and reducing disease burden. This approach excludes treatment of patients with severe AE, who should be referred to specialist care. Emphasis has been given to the importance of general skincare, patient education and the topical anti-inflammatory medications available in South Africa (TCSs and TCIs).

Indexed as

Dermatitis, AtopicAdolescentAlgorithmsChildHumansQuality of LifeSouth AfricaTacrolimusTacrolimusatopic dermatitisatopic eczemapimecrolimustacrolimustreatment algorithm

Identifiers

PMID33314940
PMCPMC8377852

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.