ReviewJournal of clinical hypertension (Greenwich, Conn.)2021
Hypertension and erectile dysfunction: The role of endovascular therapy in Asia.
Review in Journal of clinical hypertension (Greenwich, Conn.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05362994 (Feasibility and Safety of Selution SLR™ Sirolimus-eluting Balloon in Patients With Distal Internal Pudendal-penile Artery Disease and Erectile Dysfunction), which is not on this map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Feasibility and Safety of Selution SLR™ Sirolimus-eluting Balloon in Patients With Distal Internal Pudendal-penile Artery Disease and Erectile Dysfunction: : PERFECT-SELUTION First-in-man (FIM)
Who cites it
18 citing papers in PubMed, 38 citations in OpenAlex.
- Causal Relationship between Dietary-Derived Antioxidants and Erectile Dysfunction: A Mendelian Randomization Study.The world journal of men's health · 2026Article
- Article
- A narrative review of endovascular treatment in addressing arterial and venous erectile dysfunction.Frontiers in radiology · 2025Review
- The potential link between inflammatory bowel disease and male erectile dysfunction: mechanistic insights and novel therapeutic perspectives.Frontiers in immunology · 2025Review
- Metabolic Syndrome-Associated Erectile Dysfunction: Multiple Vascular Endothelial Dysfunction Mechanisms and Potential Therapeutic Targets.International journal of biological sciences · 2025Review
- Effects of Anti-Diabetic Drugs on Erectile Dysfunction: A Systematic Review and Meta-Analysis.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025Review
- 2024 Guidelines of the Taiwan Society of Cardiology on the Primary Prevention of Atherosclerotic Cardiovascular Disease --- Part II.Acta Cardiologica Sinica · 2024Article
- Article
- Treatment of sexual dysfunction induced by hyperprolactinemia accompanied by reduced luteinizing hormone levels: A case report.Clinical case reports · 2024Article
- Assessment of erectile dysfunction prevalence and associated factors in hypertensive men.PeerJ · 2024Article
- Genetically predicted cardiovascular diseases could increase the risk of erectile dysfunction: a bidirectional Mendelian randomization.World journal of urology · 2023Article
- Relationship Between Hypertension, Antihypertensive Drugs and Sexual Dysfunction in Men and Women: A Literature Review.Vascular health and risk management · 2023Review
- The flow index provides a comprehensive assessment of erectile dysfunction by combining blood flow velocity and vascular diameter.Scientific reports · 2022Article
- Psychosexual Health and Sexual Medicine in Consultation-Liaison Psychiatry.Indian journal of psychiatry · 2022Article
- The role of tadalafil in treated hypertensive patients with erectile dysfunction.Journal of clinical hypertension (Greenwich, Conn.) · 2022Article
- Advances in physical diagnosis and treatment of male erectile dysfunction.Frontiers in physiology · 2022Review
- Pathological Significance of Macrophages in Erectile Dysfunction Including Peyronie's Disease.Biomedicines · 2021Review
- Hypertension and erectile dysfunction: The role of endovascular therapy in Asia.Journal of clinical hypertension (Greenwich, Conn.) · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 10 institutions in 10 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The prevalence of erectile dysfunction (ED) is above 40% in both Asian and non-Asian male populations after the age of 40 years. The prevalence of ED among hypertensive patients is approximately double than that in normotensive population. Pelvic arterial insufficiency is the predominant cause of ED in men aged over 50 years. Stenosis in any segment of the iliac-pudendal-penile arterial system, which is considered an erectile-related arterial axis, could lead to ED. Pharmacotherapy with lifestyle modification is effective in alleviating sexual dysfunction, yet a substantial number of patients still develop ED. Given the established applicability of angioplasty for the entire iliac-pudendal-penile arterial system, penile duplex ultrasound, and pelvic computed tomography angiography could be considered as the routine screening tools in ED patients with poor response to phosphodiesterase-5 inhibitors. Endovascular therapy for pelvic arterial insufficiency-related ED has been shown to be a safe and effective treatment option in patients who have anatomically suitable vessels and functionally significant stenoses. Clinical improvement was achieved in over 60% of patients at one year following pelvic angioplasty in the PERFECT registry from Taiwan. A 30%-40% restenosis rate in distal internal pudendal and penile arteries remains a hurdle. Angioplasty for pelvic arterial occlusive disease could be considered as a viable approach to arteriogenic ED.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.