Evidence map›Paper›PMID 33314695›Full record

ArticleJournal of cellular and molecular medicine2021

Systematic evaluation, verification and comparison of tuberculosis-related non-coding RNA diagnostic panels.

Mengyuan Lyu, Yuhui Cheng, Jian Zhou, Weelic Chong, Yili Wang, Wei Xu, Binwu Ying

Open access · goldAbstract readComparative Study
In one paragraph

Article in Journal of cellular and molecular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Mengyuan LyuDepartment of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, China.
Yuhui ChengDepartment of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, China.
Jian ZhouWest China School of Medicine, Sichuan University, Chengdu, China.
Weelic ChongSidney Kimmel School of Medicine, Thomas Jefferson University, Philadelphia, PA, USA.
Yili WangDepartment of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, China.
Wei XuDepartment of Biostatistics, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
Binwu YingDepartment of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, China.ORCID 0000-0001-7828-1453
Sichuan University · CNThomas Jefferson University · USUniversity Health Network · CA

Funding

1·3·5 project for disciplines of excellence-Clinical Research Incubation Project, West China Hospital, Sichuan University 2020HXFH015National Science & Technology Pillar Program during the 13th Five-year Plan Period 2018ZX10715003
6 · The paper itself

Abstract

We systematically summarized tuberculosis (TB)-related non-coding RNA (ncRNA) diagnostic panels, validated and compared panel performance. We searched TB-related ncRNA panels in PubMed, OVID and Web of Science up to 28 February 2020, and available datasets in GEO, SRA and EBI ArrayExpress up to 1 March 2020. We rebuilt models and synthesized the results of each model in validation sets by bivariate mixed models. Specificity at 90% sensitivity, area under curve (AUC) and inconsistence index (I

Indexed as

AdolescentAdultDatabases, GeneticEthnicityGene Expression RegulationGene OntologyHumansMicroRNAsRegression AnalysisReproducibility of ResultsRNA, CircularRNA, UntranslatedTuberculosisMicroRNAsRNA, CircularRNA, Untranslateddiagnostic panelncRNAsperformancetuberculosis

Identifiers

PMID33314695
PMCPMC7810967
OpenAlexW3111587957

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.