Evidence map›Paper›PMID 33314402›Full record

ArticleHaemophilia : the official journal of the World Federation of Hemophilia2021

Managing women-specific bleeding in inherited bleeding disorders: A multidisciplinary approach.

Eveline P Mauser-Bunschoten, Rezan A Kadir, Ellen T M Laan, Petra Elfvinge, Lotte Haverman, Lorynn Teela, Manon E L Degenaar, Dietje E Fransen van de Putte, Roseline D'Oiron, Karin P M van Galen

Open access · hybridAbstract read
In one paragraph

Article in Haemophilia : the official journal of the World Federation of Hemophilia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Von Willebrand disease: more than just a bleeding disorder.Research and practice in thrombosis and haemostasis · 2026
    Review
  3. Multidisciplinary perinatal care for women with bleeding disorders.Research and practice in thrombosis and haemostasis · 2025
    Article
  4. Article
  5. Obstetric and Gynaecological Challenges and Outcomes in Women and Girls With Glanzmann's Thrombasthenia.Haemophilia : the official journal of the World Federation of Hemophilia · 2025
    Article
  6. Article
  7. Research and practice in thrombosis and haemostasis · 2024
    Review
  8. Review
  9. Article
  10. What have we learned about the patient's experience of von Willebrand disease? A focus on women.Hematology. American Society of Hematology. Education Program · 2022
    Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 4 countries.

Eveline P Mauser-BunschotenVan Creveldkliniek, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Rezan A KadirKatharine Dormandy Haemophilia and Thrombosis Unit, Department of Obstetrics and Gynaecology, Royal Free Foundation Hospital and Insitiute for Women's Health, University College London, London, UK.ORCID https://orcid.org/0000-0002-2684-1006
Ellen T M LaanDepartment of Sexology and Psychosomatic Gynaecology, Amsterdam University Medical Center, Amsterdam, The Netherlands.
Petra ElfvingeDepartment of Haematology, Karolinska University, Stockholm, Sweden.
Lotte HavermanDepartment of Psychology, Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Lorynn TeelaDepartment of Psychology, Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Manon E L DegenaarDutch Haemophilia Patient Society NVHP, Nijkerk, The Netherlands.
Dietje E Fransen van de PutteDepartment of Genetics, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Roseline D'OironAPHP Paris Saclay, Hôpital Bicêtre, INSERM U 1176, Le Kremlin Bicêtre, France.ORCID https://orcid.org/0000-0002-4843-7805
Karin P M van GalenVan Creveldkliniek, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.ORCID https://orcid.org/0000-0003-3251-8595
Utrecht University · NLEmma Kinderziekenhuis · NLDutch Cancer Society · NLInserm · FRKarolinska University Hospital · SERoyal Free London NHS Foundation Trust · GBUniversity of Amsterdam · NL

Funding

European Association for Haemophilia and Allied Disorders
6 · The paper itself

Abstract

introductionMultidisciplinary management of women-specific bleeding is important to preserve quality of life, healthy reproduction and social participation of women and girls with bleeding disorders (WBD).

aimTo support appropriate multidisciplinary care for WBD in haemophilia treatment centres.

methodsTwo case examples are presented and management issues discussed from different health care perspectives, including the nurse, patient, psychologist, gynaecologist, geneticist, psychosexual therapist and haematologist.

resultsWoman with bleeding disorders may experience heavy menstruation from menarche onwards. This has a physical and psychosocial impact requiring a multidisciplinary approach. If a woman with an inherited bleeding disorder desires to become pregnant, preconception counselling is essential, to discuss genetic diagnosis, state of the art treatment options for the bleeding disorder in question and possible choices to prevent having an affected child, as well as maternal bleeding risks during conception, delivery and the post-partum period.

conclusionAdequate management and good education of WBD requires a patient-centred multidisciplinary approach with experienced specialists in a haemophilia treatment centre.

Indexed as

GynecologyHemophilia AMenorrhagiaChildFemaleHemorrhageHumansPregnancyQuality of Lifebleeding disorderhaemophiliaheavy menstrual bleedingpost-partum haemorrhage and reproductionvon willebrand diseasewomen

Identifiers

PMID33314402
PMCPMC8246991
OpenAlexW3112047146

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.