ArticleCardiovascular intervention and therapeutics2022
Early hemodynamic changes after transcatheter aortic valve implantation in patients with severe aortic stenosis measured by invasive pressure volume loop analysis.
Article in Cardiovascular intervention and therapeutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 16 citations in OpenAlex.
- Acute bi-ventricular haemodynamic changes after transcatheter aortic valve implantation for severe aortic stenosis assessed using invasive pressure-volume loops.Cardiovascular intervention and therapeutics · 2026Article
- Early Enhancement of Mitral Annular e' Following Transcatheter Aortic Valve Implantation: The Role of Early Diastolic Filling.Echocardiography (Mount Kisco, N.Y.) · 2026Article
- Phase-dependent agreement between noninvasive and invasive blood pressure monitoring during transcatheter aortic valve replacement: a prospective observational study.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2026Observational
- Article
- Stroke in Transcatheter Aortic Valve Implantation (TAVI): A Comprehensive Review.Journal of clinical medicine · 2025Review
- Impact of Left Ventricular Diastolic Pressure Changes on Clinical Outcomes After Transcatheter Aortic Valve Replacement.Journal of the American Heart Association · 2025Observational
- Changes in afterload and contractility in patients with severe aortic stenosis after transcatheter aortic valve replacement.European heart journal. Imaging methods and practice · 2025Article
- Noninvasive Hemodynamic Evaluation Following TAVI for Severe Aortic Stenosis.Journal of the American Heart Association · 2023Article
- Invasive Real Time Biventricular Pressure-Volume Loops to Monitor Dynamic Changes in Cardiac Mechanoenergetics During Structural Heart Interventions: Design and Rationale of a Prospective Single-Center Study.Structural heart : the journal of the Heart Team · 2022Article
- Acute haemodynamic impact of transcatheter aortic valve implantation in patients with severe aortic stenosis.ESC heart failure · 2022Article
- Improvement of hemodynamic parameters in aortic stenosis patients with transcatheter valve replacement by using impedance cardiography.Frontiers in cardiovascular medicine · 2022Article
- Cardiac Structural Remodeling and Hemodynamic Patterns Following Transcatheter Aortic Valve Replacement.Cureus · 2021Article
- Ventricular pressure-volume loop and other heart-function metrics can elucidate etiology of failure of TAVI and interventions.REC, interventional cardiologyArticle
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Replacement of a stenotic aortic valve reduces immediately the ventricular to aortic gradient and is expected to improve diastolic and systolic left ventricular function over the long term. However, the hemodynamic changes immediately after valve implantation are so far poorly understood. Within this pilot study, we performed an invasive pressure volume loop analysis to describe the early hemodynamic changes after transcatheter aortic valve implantation (TAVI) with self-expandable prostheses. Invasive left ventricular pressure volume loop analysis was performed in 8 patients with aortic stenosis (mean 81.3 years) prior and immediately after transfemoral TAVI with a self-expandable valve system (St. Jude Medical Portico Valve). Parameters for global hemodynamics, afterload, contractility and the interaction of the cardiovascular system were analyzed. Left ventricular ejection fraction, (53.9% vs. 44.8%, p = 0.018), preload recruitable stroke work (68.5 vs. 44.8 mmHg, p = 0.012) and end-systolic elastance (3.55 vs. 2.17, p = 0.036) both marker for myocardial contractility declined significantly compared to baseline. As sign of impaired diastolic function, TAU, a preload-independent measure of isovolumic relaxation (37.3 vs. 41.8 ms, p = 0.018) and end-diastolic pressure (13.1 vs. 16.4 mmHg, p = 0.015) raised after valve implantation. Contrarily, a smaller ratio of end-systolic to arterial elastance (ventricular-arterial coupling) indicates an improvement of global cardiovascular energy efficiency (1.40 vs. 0.97 p = 0.036). Arterial elastance had a strong correlation with the number of conducted rapid ventricular pacings (Pearson correlation coefficient, r = 0.772, p = 0.025). Invasive left ventricular pressure volume loop analysis revealed impaired systolic and diastolic function in the early phase after TAVI with self-expandable valve for the treatment of severe aortic stenosis. Contrarily, we found indications for early improvement of global cardiovascular energy efficiency.
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