Evidence map›Paper›PMID 33313838›Full record

ArticleRheumatology (Oxford, England)2021

A comparison of physical function instruments in psoriatic arthritis: HAQ-DI vs MDHAQ vs PROMIS10 global physical health.

Marilyn T Wan, Jessica A Walsh, Ethan T Craig, M Elaine Husni, Jose U Scher, Soumya M Reddy, Ying-Ying Leung, Alexis Ogdie

Abstract readComparative Study
In one paragraph

Article in Rheumatology (Oxford, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
  2. Construct validity and responsiveness of EQ-5D-3L and EQ VAS in psoriatic arthritis: an evaluation based on the Swedish Rheumatology Quality Register.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Marilyn T WanDepartment of Dermatology.
Jessica A WalshDivision of Rheumatology, University of Utah.
Ethan T CraigDivision of Rheumatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.
M Elaine HusniDivision of Rheumatology, Cleveland Clinic, Cleveland, OH.
Jose U ScherDivision of Rheumatology, New York University School of Medicine, New York, NY, USA.
Soumya M ReddyDivision of Rheumatology, New York University School of Medicine, New York, NY, USA.
Ying-Ying LeungDepartment of Rheumatology & Immunology, Singapore General Hospital, Singapore, Singapore.
Alexis OgdieDivision of Rheumatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.ORCID 0000-0002-4639-0775

Funding

Utah Center for Clinical and Translational ScienceUL1TR002538 · NCATS · UNIVERSITY OF UTAH · PI HESS, RACHEL, MAJERSIK, JENNIFER JUHL · 2018 to 2022
$26.0M
Refining Outcome Measurement in Psoriatic Arthritis: Preparation for Pragmatic TrialsR01AR072363 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI OGDIE, ALEXIS R. · 2017 to 2019
$709k
NCATS NIH HHS UL1 TR002538NIAMS NIH HHS R01 AR072363
6 · The paper itself

Abstract

objectivesPhysical function is a core outcome in PsA. We examined the construct validity and responsiveness of three commonly used instruments to assess physical function in PsA: HAQ disability index (HAQ-DI), MultiDimensional HAQ (MDHAQ) and the Patient-Reported Outcomes Measurement Information System (PROMIS®) Global-10.

methodsBetween 2016 and 2019, patients with PsA were enrolled in the Psoriatic Arthritis Research Consortium longitudinal cohort study in the USA. Correlations were calculated at baseline and among change scores using Spearman's correlation coefficient. Standardized response means were calculated. Agreement with the 20% improvement cut-off was used to determine the potential effect of using MDHAQ or the PROMIS Global-10 physical health (GPH) subscore in place of HAQ-DI when assessing the ACR20.

resultsA total of 274 patients were included in the analysis. The mean age of patients was 49 years and 51% were male. At baseline, the mean HAQ-DI was 0.6 (s.d. 0.6; range 0-3), the mean MDHAQ was 1.8 (s.d. 1.6; range 0-10) and the mean GPH T-score was 43.4 (s.d. 9.3; range 0-100). All three instruments were strongly correlated at baseline (rho 0.75-0.85). Change scores were moderately correlated (rho 0.42-0.71). Among therapy initiators, the mean change between two visits in HAQ-DI, MDHAQ and GPH was -0.1 (s.d. 0.4), -0.2 (s.d. 1.2) and 2.5 (s.d. 6.1), respectively. The standardized response means were 0.18, 0.16 and 0.41, respectively.

conclusionThe three instruments tested are not directly interchangeable but have overall similar levels of responsiveness.

Indexed as

Activities of Daily LivingDisability EvaluationAdultArthritis, PsoriaticFemaleHealth StatusHealth Status IndicatorsHumansMaleMiddle AgedPatient Reported Outcome MeasuresReproducibility of ResultsSeverity of Illness Indexpatient-reported outcomesPsA

Identifiers

PMID33313838
PMCPMC8599834

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.