ArticlePain medicine (Malden, Mass.)2020
Whole Health Options and Pain Education (wHOPE): A Pragmatic Trial Comparing Whole Health Team vs Primary Care Group Education to Promote Nonpharmacological Strategies to Improve Pain, Functioning, and Quality of Life in Veterans-Rationale, Methods, and Implementation.
Article in Pain medicine (Malden, Mass.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04330365 (Implementation of a Pragmatic Trial of Whole Health Team vs. Primary Care Group Education to Promote Non-Pharmacological Strategies to Improve Pain, Functioning, and Quality of Life in Veterans), which is not on this map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Implementation of a Pragmatic Trial of Whole Health Team vs. Primary Care Group Education to Promote Non-Pharmacological Strategies to Improve Pain, Functioning, and Quality of Life in Veterans
Who cites it
21 citing papers in PubMed, 29 citations in OpenAlex.
- Baseline characteristics of Veterans from improving Veteran access to integrated management of back pain (AIM-Back) - an embedded pragmatic, cluster-randomized trial in the United States.Pain management · 2026Trial
- Natural Product Use Among Veterans with Chronic Pain: A Qualitative Study of Attitudes and Communication with Healthcare Providers.Journal of general internal medicine · 2024Trial
- Integration of Health Coaches in a Whole Health Team Model of Chronic Pain Care: a Qualitative Study.Journal of general internal medicine · 2023Trial
- Partner engagement for planning and development of non-pharmacological care pathways in the AIM-Back trial.Clinical trials (London, England) · 2023Trial
- Impact of complex, partially nested clustering in a three-arm individually randomized group treatment trial: A case study with the wHOPE trial.Clinical trials (London, England) · 2022Trial
- Article
- Optimizing diversity, equity and inclusion in pragmatic clinical trials: Findings from the Pain Management Collaboratory.The journal of pain · 2025Article
- Treatment Choices and Healthcare Services Utilization Amongst Lumbosacral Radiculopathy Patients: Results from a Randomized Controlled Trial.OBM integrative and complimentary medicine · 2025Article
- Implementation, intervention, and downstream costs for implementation of a multidisciplinary complex pain clinic in the Veterans Health Administration.Health services research · 2024Article
- Impact of the COVID-19 pandemic on participants in pragmatic clinical trials for chronic pain: implications for trial outcomes and beyond.Pain medicine (Malden, Mass.) · 2024Article
- Recommendations for monitoring adherence and fidelity in pragmatic trials based on experience in the Pain Management Collaboratory.Pain medicine (Malden, Mass.) · 2024Article
- Pragmatic clinical trials as hybrid effectiveness-implementation studies to shrink the evidence-to-practice gap for chronic pain management.Pain medicine (Malden, Mass.) · 2024Article
- Adapting to change: experiences and recommendations from the Pain Management Collaboratory on modifying statistical analysis plans.Pain medicine (Malden, Mass.) · 2024Article
- Integrated multicomponent interventions to support healthy aging of the whole person.Aging cell · 2024Article
- Intervention Fidelity in Pain Pragmatic Trials for Nonpharmacologic Pain Management: Nuanced Considerations for Determining PRECIS-2 Flexibility in Delivery and Adherence.The journal of pain · 2023Article
- Sense of loneliness of veterans in Southern Iran: a cross-sectional study.BMC public health · 2023Article
- Whole Health in Parts: Omissions from National Data Sets.Population health management · 2023Article
- Meeting the Needs of Rural Veterans: A Qualitative Evaluation of Whole Health Coaches' Expanded Services and Support during COVID-19.International journal of environmental research and public health · 2022Article
- Justice and equity in pragmatic clinical trials: Considerations for pain research within integrated health systems.Learning health systems · 2022Article
- Natural Product Use for Chronic Pain: A New Survey of Patterns of Use, Beliefs, Concerns, and Disclosure to Providers.Global advances in integrative medicine and healthArticle
Corrections and comments
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Authors and funding
27 authors at 13 institutions in 1 country.
Funding
Abstract
backgroundThe Whole Health model of the U.S. Department of Veterans Affairs (VA) emphasizes holistic self-care and multimodal approaches to improve pain, functioning, and quality of life. wHOPE (Whole Health Options and Pain Education) seeks to be the first multisite pragmatic trial to establish evidence for the VA Whole Health model for chronic pain care.
designwHOPE is a pragmatic randomized controlled trial comparing a Whole Health Team (WHT) approach to Primary Care Group Education (PC-GE); both will be compared to Usual VA Primary Care (UPC). The WHT consists of a medical provider, a complementary and integrative health (CIH) provider, and a Whole Health coach, who collaborate with VA patients to create a Personalized Health Plan emphasizing CIH approaches to chronic pain management. The active comparator, PC-GE, is adapted group cognitive behavioral therapy for chronic pain. The first aim is to test whether the WHT approach is superior to PC-GE and whether both are superior to UPC in decreasing pain interference in functioning in 750 veterans with moderate to severe chronic pain (primary outcome). Secondary outcomes include changes in pain severity, quality of life, mental health symptoms, and use of nonpharmacological and pharmacological therapies for pain. Outcomes will be collected from the VA electronic health record and patient-reported data over 12 months of follow-up. Aim 2 consists of an implementation-focused process evaluation and budget impact analysis. SUMMARY: This trial is part of the Pain Management Collaboratory, which seeks to create national-level infrastructure to support evidence-based nonpharmacological pain management approaches for veterans and military service personnel.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.